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Horizontal transfer of matrix metalloproteinase genes links early animal and microbial evolution. [PDF]
Parsons C, Fournier GP.
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Metallic elements and their molecular roles in gastric cancer: Pathogenic mechanisms and therapeutic implications. [PDF]
Jing LB +5 more
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The extracellular matrix: structure, composition, biological functions, diseases, and therapeutic targets. [PDF]
Kamal KM +6 more
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Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma
Virchows Archiv, 2009Merkel cell carcinoma (MCC) is an aggressive cutaneous tumor with poor outcome and increasing incidence. We examined by immunohistochemistry the expression of three novel matrix metalloproteinases (MMPs)-MMP-21, MMP-26, and MMP-28-in 44 primary MCC tumors and six lymph node metastases while MMP-10 served as a positive control. Their mRNA expression was
Sari, Suomela +5 more
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Matrix Metalloproteinase (MMP)-7 Activates MMP-8 But Not MMP-13
Medicinal Chemistry, 2006Matrix Metalloproteinases (MMPs) are a class of zinc-dependent enzymes that degrade extracellular matrix components, particularly collagen. MMPs have been implicated in a diverse list of pathological processes, including cancer and cardiovascular disease.
S, Dozier, G P, Escobar, M L, Lindsey
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Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis
Scandinavian Journal of Gastroenterology, 2010Matrix metalloproteinases (MMPs) are considered the predominant proteases in the pathogenesis of mucosal ulcerations associated with inflammatory bowel disease (IBD). Whether the malignancy associated MMP-7 and MMP-13 or the recently cloned MMP-28 convey a certain meaning for intestinal homeostasis and pathogenesis of IBD is currently unknown.
Timo, Rath +5 more
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