Results 71 to 80 of about 15,502 (266)

MEMS-Based Vibration Acquisition for Modal Parameter Identification of Substation Frame

Applied Sciences
As a critical component of substations, the substation frames are characterized by significant height and span, which presents substantial challenges and risks in conducting dynamic response tests using traditional sensors. To simplify these difficulties,
Ruochen Qiang, Ming Sheng, Dongxu Su, Yachen Wang, Xianghong Liu, Qing Sun   +5 more
doaj   +1 more source

Recursive Method in Modal Parameter Identification of Aerospace Structures under Non-Gaussian Noise

Shock and Vibration, 2020
Operational modal parameter identification is a tough problem in aerospace engineering due to the complex mechanics environment, various noises, and limited computational resources.
Lei Yu, Yong-li Zhang, Meng-di Yuan, Rui-qing Liu, Qi Zhang   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Research of the Operational Modal Parameter Identification Technology and Application based on QICA

Jixie chuandong, 2015
Aiming at the major difficulties of OMA method based on vibration signals such as low noise-robust ability,high subjective experience and poor accuracy in identifying parameters and more complex recognition method,a new method of OMA on the basis of QICA
Zhang Rui, He Changde, Huang Jinying, Zhang Yongmei, Xue Chenyang, Zhang Wendong   +5 more
doaj  

Fatigue damage identification by means of modal parameters

Procedia Engineering, 2011
AbstractObject of the present paper is an experimental investigation about high cycles fatigue damage and corresponding variation of modal parameters (internal damping and resonance frequency) in steel specimens. On the basis of a modal approach, a mixed technique has been developed in order to relate fatigue damage and intrinsic properties of the ...
CURA', Francesca Maria, GALLINATTI, ALESSANDRA ELEONORA   +1 more
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Identification of characteristic parameters of layered structures using modal parameters

Mechanical Engineering Journal
In this study, we present a method for determining parameters that are essential for evaluating the health of layered structures. This method uses modal parameters to identify characteristic parameters that can accurately reproduce the measured modal damping ratio. Specifically, the proposed method uses natural frequencies, natural vibration modes, and
Daiki TAJIRI, Shozo KAWAMURA
openaire   +2 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Modal Parameter Recursive Estimation of Concrete Arch Dams under Seismic Loading Using an Adaptive Recursive Subspace Method

Sensors
Modal parameter estimation is crucial in vibration-based damage detection and deserves increased attention and investigation. Concrete arch dams are prone to damage during severe seismic events, leading to alterations in their structural dynamic ...
Xinyi Zhu, Jianchun Qiu, Yanxin Xu, Xingqiao Chen, Pengcheng Xu, Xin Wu, Shaolong Guo, Jicheng Zhao, Jiale Lin   +8 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source