Results 91 to 100 of about 4,040,361 (305)

A Practical Environment to Apply Model-Driven Web Engineering [PDF]

open access: yes, 2009
The application of a model-driven paradigm in the development of Web Systems has yielded very good research results. Several research groups are defining metamodels, transformations, and tools which offer a suitable environment, known as model-driven ...
Escalona Cuaresma, María José   +7 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Effect of distributed energy systems on the electricity grid [PDF]

open access: yes, 2011
A feasibility study is being carried out at Ecotricity into a distributed energy storage system comprising Energy stores (batteries) placed at consumer level (in customer’s homes).
L., MacManus, M., Brown
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Designing an engineering construction standards system for energy and environment sustainability: based on model-based systems engineering

open access: yesFrontiers in Environmental Science
With the world facing increasingly severe environmental and energy challenges, the role of the construction industry in achieving the dual-carbon goals has become increasingly prominent.
Song Han, Xiaoyu Wang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Development of a Body Weight Support System Employing Model-Based System Engineering Methodology

open access: yesTechnologies
Partial body weight support systems have proven to be a vital tool in performing physical therapy for patients with lower limb disabilities to improve gait.
Alberto E. Loaiza   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Model-Based System Engineering Adoption in the Vehicular Systems Domain [PDF]

open access: yesAnnals of computer science and information systems, 2022
Henrik Gustavsson   +2 more
doaj   +1 more source

Engineering model system study for a regenerative fuel cell: Study report [PDF]

open access: yes
Key design issues of the regenerative fuel cell system concept were studied and a design definition of an alkaline electrolyte based engineering model system or low Earth orbit missions was completed.
Chang, B. J.   +3 more
core   +1 more source

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