Results 91 to 100 of about 45,910,073 (298)
Mapping customer needs to engineering characteristics: an aerospace perspective for conceptual design [PDF]
, 2014 Designing complex engineering systems, such as an aircraft or an aero-engine, is immensely challenging. Formal Systems Engineering (SE) practices are widely used in the aerospace industry throughout the overall design process to minimise the overall ...
Eres, M.H. +8 more
core +1 more source
UTILIZING A MODEL-BASED SYSTEMS ENGINEERING APPROACH TO DEVELOP A COMBAT SYSTEM PRODUCT LINE [PDF]
, 2018 Current U.S. Navy combat system suites are ship class dependent. There are a variety of configurations that include sensors, weapons, and system interfaces to accomplish similar goals.
Hall, Robert
core +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Model-Based System Engineering Adoption in the Vehicular Systems Domain [PDF]
Annals of computer science and information systems, 2022 Henrik Gustavsson +2 more
doaj +1 more source
Modeling- and Simulation-Driven Methodology for the Deployment of an Inland Water Monitoring System
InformationIn response to the challenges introduced by global warming and increased eutrophication, this paper presents an innovative modeling and simulation (M&S)-driven model for developing an automated inland water monitoring system. This system is grounded in a
Giordy A. Andrade +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Simulation-based Bayesian optimal ALT designs for model discrimination [PDF]
, 2015 Accelerated life test (ALT) planning in Bayesian framework is studied in this paper with a focus of differentiating competing acceleration models, when there is uncertainty as to whether the relationship between log mean life and the stress variable is ...
core +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
V-Model Role Engineering [PDF]
The paper focuses on role engineering which is an important topic in the development of access control system, particularly when considering Role Based Access Control – RBAC models.
Radu CONSTANTINESCU
core
A Systems Thinking Approach to Designing Clinical Models and Healthcare Services
Systems, 2019 Chronic diseases are on the rise, increasing in number and treatment regimen complexity. Consequently, the needs of patients with chronic diseases are increasing and becoming more complex and multi-faceted.
Inas S. Khayal
doaj +1 more source