Results 91 to 100 of about 1,285,257 (315)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

UTILIZING A MODEL-BASED SYSTEMS ENGINEERING APPROACH TO DEVELOP A COMBAT SYSTEM PRODUCT LINE [PDF]

, 2018
Current U.S. Navy combat system suites are ship class dependent. There are a variety of configurations that include sensors, weapons, and system interfaces to accomplish similar goals.
Hall, Robert
core  

Data-driven adaptive model-based predictive control with application in wastewater systems [PDF]

, 2011
This study is concerned with the development of a new data-driven adaptive model-based predictive controller (MBPC) with input constraints. The proposed methods employ subspace identification technique and a singular value decomposition (SVD)-based ...
R. Katebi, N.A. Wahab, Katebi, M.R., Wahab, N.A., M.F. Rahmat, Rahmat, M.F., J. Balderud, Balderud, J.   +7 more
core   +1 more source

Creative Engineering Study Based on System Approch

آموزش مهندسی ایران, 2009
An engineer is known as a creative person, and engineering is defined as a creative activities. This definition could open a window toward the engineering education.
Abdollah Sadri
doaj   +1 more source

Effectiveness of Engineering Service Organizations in Global Projects Execution

Mechanics and Advanced Technologies, 2020
Possibilities to maximize the efficiency of Service Engineering Organizations involvement are evaluated. Highlighted the importance to consider several specific features of Engineering Service companies in order to maintain the high efficiency of the ...
Aleksei Stepin
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Adaptable MBSE Problem Definition with ARMADE: Perspectives from Firefighting and AAM SoS Environments

Engineering Proceedings
Model-based systems engineering (MBSE) offers significant advantages over traditional document-based approaches, particularly in improving the clarity, traceability, and efficiency of requirements engineering (RE).
Adrian Chojnacki, Giuseppa Donelli, Luca Boggero, Prajwal S. Prakasha, Björn Nagel   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Model-Based Space Engineering Ontology [PDF]

, 2016
<p>This resource contains an ontology built for supporting the design of space systems in the scope of model-based systems engineering (MBSE). In MBSE, a conceptual model is shared across engineering disciplines involved in a project
Eisenmann, Harald, Hennig, Christian (5287282), Hennig, Christian, Eisenmann, Harald (5287279)   +3 more
core   +1 more source

Designing an engineering construction standards system for energy and environment sustainability: based on model-based systems engineering

Frontiers in Environmental Science
With the world facing increasingly severe environmental and energy challenges, the role of the construction industry in achieving the dual-carbon goals has become increasingly prominent.
Song Han, Xiaoyu Wang
doaj   +1 more source