Results 71 to 80 of about 3,497,010 (299)

The model and method of SCADA diagnostics as an object with partially defined parameters [PDF]

, 2017
Modern SCADA are widely spread all over the world to control technological processes in different industries such as power engineering, military, transport, etc.
Syrotkina, O.
core   +4 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Engineering Systems with Standards and Digital Models: Development of a 15288-SysML Grid

Systems
The paradigm shift that has spurred the fourth industrial revolution, in what is termed Industry 4.0, has ushered in the need to adopt digital technologies throughout the worldwide industrial base to support system design efforts. The adoption of digital
Kevin MacG. Adams, Irfan Ibrahim, Steven Krahn   +2 more
doaj   +1 more source

Microservices and Machine Learning Algorithms for Adaptive Green Buildings [PDF]

, 2019
In recent years, the use of services for Open Systems development has consolidated and strengthened. Advances in the Service Science and Engineering (SSE) community, promoted by the reinforcement of Web Services and Semantic Web technologies and the ...
Alonso Montesinos, Joaquín Blas, Ayala Palenzuela, Rosa María, Capobianco Uriarte, María De Las Mercedes, Criado Rodríguez, Javier, Iribarne Martínez, Luis Fernando, Piedra Fernández, José Antonio, Rodríguez Gracia, Diego   +6 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Open-Source Data Formalization through Model-Based Systems Engineering for Concurrent Preliminary Design of CubeSats

Aerospace
Market trends in the space sector suggest a notable increase in satellite operations and market value for the coming decade. In parallel, there has been a shift in the industrial and academic sectors from traditional Document-Based System Engineering to ...
Giacomo Luccisano, Sophia Salas Cordero, Thibault Gateau, Nicole Viola   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Product Cost Calculation in Model-Based Systems Engineering

Systems
In product development, costs play a major role in making design decisions. As such, it is desirable to have this information as early as possible in the product development process (PDP).
Georg Hartmann, Thilo Zerwas, Lisa Domröse, Kathrin Boelsen, Christian Hilger, Simon Schnürer   +5 more
doaj   +1 more source

A component-oriented programming framework for developing embedded mobile robot software using PECOS model [PDF]

, 2006
A practical framework for component-based software engineering of embedded real-time systems, particularly for autonomous mobile robot embedded software development using PECOS component model is proposed The main features of this framework are: (1) use ...
Abang Jawawi, Dayang Norhayati, Deris, Safaai, Mamat, Rosbi   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source