Results 31 to 40 of about 151,713,479 (253)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

State space model identification using model reference adaptive approach: software and hardware-in-the-loop simulation

open access: yesCogent Engineering
This paper presents a comprehensive tutorial on the identification process for a class of continuously dynamic systems expressed in state-space form using the model reference adaptive approach.
Van Tu Duong   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Parameterizing the microbial loop: an experiment in reducing model complexity [PDF]

open access: yes, 2004
The structure of the plankton food web in the upper mixed layer has important implications for the export of biogenic material from the euphotic zone. While the action of the microbial loop causes material to be recycled near the surface, activity of the
Challenor, P.G.   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Energy Management Optimization and Validation of a Hydrogen Fuel Cell-Powered Agricultural Tractor Based on Hierarchical Dynamic Programming

open access: yesIEEE Access
In addressing challenges associated with the constrained enhancement of range performance in pure electric tractors, the difficulty in achieving genuinely eco-friendly agricultural machinery with hybrid powertrains, and the outdated approaches to energy ...
Yanying Li   +4 more
doaj   +1 more source

Path Tracking Control of Autonomous Vehicle Based on Nonlinear Tire Model

open access: yesActuators, 2021
The tire forces of vehicles will fall into the non-linear region under extreme handling conditions, which cause poor path tracking performance. In this paper, a model predictive controller based on a nonlinear tire model is designed.
Fen Lin   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Real time implementation for robust adaptive sliding mode predictive control of PMSM

open access: yesUnconventional Resources
Model Predictive Control is recognized as a promising approach for electric drives, with particular interest in the development of robust and high-performance predictive models.
Rachid Ibrahimi   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy