Results 51 to 60 of about 151,713,479 (253)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Model-in-the-Loop Simulation for Model Predictive Controlled High-Pressure Direct Injection Dual-Fuel Engine Combustion Control

Designs
Given the intricate combustion process and the multitude of control parameters inherent to the high-pressure direct injection (HPDI) diesel/natural gas dual-fuel engine, achieving precise combustion control represents a significant challenge.
Xiuyun Shuai, Hongyu Liu, He Li, Wei Cui, Qingxin Wang, Wenbin Yu, Feiyang Zhao   +6 more
doaj   +1 more source

A Model-Based Approach for Bridging Virtual and Physical Sensor Nodes in a Hybrid Simulation Framework

Sensors, 2014
The Model Based Design (MBD) approach is a popular trend to speed up application development of embedded systems, which uses high-level abstractions to capture functional requirements in an executable manner, and which automates implementation code ...
Mohammad Mozumdar, Zhen Yu Song, Luciano Lavagno, Alberto L. Sangiovanni-Vincentelli   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Reducing Step Size of Hardware-in-Loop Simulation in Electro-Dynamic Shaker Controller Design by Electrical- Mechanical Analogy

IEEE Access
Shaker is the key facility of the vibration test system. The wide frequency band of the vibration signal poses a challenge on the shaker controller design, therefore a hardware in loop (HIL) test is desired to verify the controller performance before it ...
Guoyuan Liu, Zemin Pan, Liang Chen
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Validation of Sliding Mode and Passivity Control in High-Power Quadratic Buck Converter Through Rapid Prototyping

IEEE Access
This document introduces a rapid control prototyping (RCP) approach applied to the industrial sector using a non-linear Quadratic Buck Converter (QBC) DC-DC.
Rafael Antonio Acosta-Rodriguez, Fredy Hernan Martinez-Sarmiento, German Ardul Munoz-Hernandez, Gerardo Mino-Aguilar, Edgar Alfredo Portilla-Flores, Paola Andrea Nino-Suarez, Octavio Jose Salcedo-Parra   +6 more
doaj   +1 more source

Improving the Stability and Accuracy of Power Hardware-in-the-Loop Simulation Using Virtual Impedance Method

Energies, 2016
Power hardware-in-the-loop (PHIL) systems are advanced, real-time platforms for combined software and hardware testing. Two paramount issues in PHIL simulations are the closed-loop stability and simulation accuracy.
Xiaoming Zha, Chenxu Yin, Jianjun Sun, Meng Huang, Qionglin Li   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Sub-series 2: Publications

, 1963
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Daniels, Tim
core   +1 more source