Results 1 to 10 of about 957,044 (346)
Mouse models in colon cancer, inferences, and implications
iScience, 2023 Summary: Mouse models of colorectal cancer (CRC) have been crucial in the identification of the role of genes responsible for the full range of pathology of the human disease and have proved to be dependable for testing anti-cancer drugs. Recent research
Melanie Haas Kucherlapati
doaj +1 more source
SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis
iScience, 2022 Summary: Recent studies showed that SARS-CoV-2 can infect adult human pancreas and trigger pancreatic damage. Here, using human fetal pancreas samples and 3D differentiation of human pluripotent cells into pancreatic endocrine cells, we determined that ...
Wojciech J. Szlachcic +12 more
doaj +1 more source
模式生物斑马鱼在卒中研究中的应用Application of Zebrafish Model Organism in Stroke Research
Zhongguo cuzhong zazhi, 2022 Animal model provides a necessary tool for exploring the complex pathophysiological process of cerebrovascular disease and drug development. Zebrafish (Danio rerio) is an ideal spinal model organism, which has the characteristics of small size, strong ...
莫东灿, 刘柳余, 李肖玲, 李建立, 罗曼
doaj +1 more source
Brain-Body Control of Glucose Homeostasis—Insights From Model Organisms
Frontiers in Endocrinology, 2021 Tight regulation of blood glucose is essential for long term health. Blood glucose levels are defended by the correct function of, and communication between, internal organs including the gastrointestinal tract, pancreas, liver, and brain.
Alastair J. MacDonald +4 more
doaj +1 more source
The Norway rat, from an obnoxious pest to a laboratory pet
eLife, 2020 The laboratory rat was the first mammal domesticated for research purposes. It is descended from wild Norway rats, Rattus norvegicus, which despite their name likely originated in Asia.
Klaudia Modlinska, Wojciech Pisula
doaj +1 more source
Amphioxus as a model to study the evolution of development in chordates
eLife, 2023 Cephalochordates and tunicates represent the only two groups of invertebrate chordates, and extant cephalochordates – commonly known as amphioxus or lancelets – are considered the best proxy for the chordate ancestor, from which they split around 520 ...
Salvatore D'Aniello +2 more
doaj +1 more source
Insect Models in Nutrition Research
Biomolecules, 2022 Insects are the most diverse organisms on earth, accounting for ~80% of all animals. They are valuable as model organisms, particularly in the context of genetics, development, behavior, neurobiology and evolutionary biology. Compared to other laboratory
Miray Tonk-Rügen +2 more
doaj +1 more source
mSphere, 2020 Saccharomyces cerevisiae has been frequently used to study biogenesis, functionality, and intracellular transport of various renal proteins, including ion channels, solute transporters, and aquaporins.
Hasib A. M. Sarder +5 more
doaj +1 more source
WormBase: A modern Model Organism Information Resource [PDF]
, 2020 WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes.
et al,, Harris, Todd W, Schedl, Tim
core +5 more sources
Journal of Biological Research, 2018 Compounds known as chemical mediators, including acetylcholine, have been found not only in humans and animals, but also in living organisms, like protozoa, which lack nervous system.
Francesca Sardi +5 more
doaj +1 more source