Results 101 to 110 of about 27,460,944 (326)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Unraveling the Dynamics of Host–Microbiota Indole Metabolism: An Investigation of Indole, Indolin-2-one, Isatin, and 3-Hydroxyindolin-2-one

Molecules
The gut microbiota produces a variety of bioactive molecules that facilitate host–microbiota interaction. Indole and its metabolites are focused as possible biomarkers for various diseases.
Arnas Kunevičius, Mikas Sadauskas, Julija Raudytė, Rolandas Meškys, Aurelijus Burokas   +4 more
doaj   +1 more source

Capturing the essence of folding and functions of biomolecules using Coarse-Grained Models

, 2011
The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example during chromosome organization. Describing phenomena that cover such diverse length,
A Dhar, A Elcock, A Elcock, A Grosberg, A Grosberg, A Minton, A Pisliakov, A Podtelezhnikov, A Rychkova, A Savelyev, A Vologodskii, AA Podtelezhnikov, B Messer, BJ Alder, C Bustamante, C Clementi, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, C Hyeon, D Thirumalai, D Thirumalai, D Thirumalai, D Thirumalai, D Thirumalai, E Koculi, E Lieberman-Aiden, E O'Brien, E Shakhnovich, EP O'Brien, F Valle, G Lorimer, G Papoian, G Ziv, H Liu, H Ma, HX Zhou, I Tinoco Jr., J Chen, J Harms, J Karanicolas, J Straub, JD Honeycutt, JM Fernandez, JN Onuchic, KA Dill, M Levitt, M Mickler, M Strajbl, M Takano, ME Fisher, MJ Todd, MS Cheung, N Hirokawa, N Koga, N Toan, OK Dudko, P Weinkam, PB Moore, PC Whitford, Q Du, R Russell, R Tehver, R Tehver, RD Vale, RD Vale, RI Dima, RW Pastor, S Jun, S Jun, S Jun, S Kamerlin, S Kirkpatrick, S Moghaddam, SB Smith, SJ Chen, SJ Marrink, T Cloutier, T Cremer, T Kirkpatrick, T Veitshans, V Lubchenko, Z Liu, Z Xu   +89 more
core   +1 more source

Insights into Protein–Ligand Interactions: Mechanisms, Models, and Methods

International Journal of Molecular Sciences, 2016
Molecular recognition, which is the process of biological macromolecules interacting with each other or various small molecules with a high specificity and affinity to form a specific complex, constitutes the basis of all processes in living organisms ...
Xing Du, Yi Li, Yuan-Ling Xia, Shi-Meng Ai, Jing Liang, Peng Sang, Xing-lai Ji, Shu-Qun Liu   +7 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Draft genome sequence data of Lactiplantibacillus plantarum 33C isolated from Lithuanian fermented food

Data in Brief
This strain was isolated from traditionally (homemade) fermented Lithuanian cherry tomatoes. The genome consists of 55 contigs with a total size of 3,326,119 bp, an N50 of 170738, and a GC% of 44.3 %.
Ashwinipriyadarshini Megur, Eglė Lastauskienė, Aurelijus Burokas   +2 more
doaj   +1 more source

3D Microporous Scaffolds Manufactured via Combination of Fused Filament Fabrication and Direct Laser Writing Ablation

Micromachines, 2014
A 3D printing fused filament fabrication (FFF) approach has been implemented for the creation of microstructures having an internal 3D microstructure geometry. These objects were produced without any sacrificial structures or additional support materials,
Mangirdas Malinauskas, Sima Rekštytė, Laurynas Lukoševičius, Simas Butkus, Evaldas Balčiūnas, Milda Pečiukaitytė, Daiva Baltriukienė, Virginija Bukelskienė, Arūnas Butkevičius, Povilas Kucevičius, Vygandas Rutkūnas, Saulius Juodkazis   +11 more
doaj   +1 more source

Slightly generalized Generalized Contagion: Unifying simple models of biological and social spreading

, 2017
We motivate and explore the basic features of generalized contagion, a model mechanism that unifies fundamental models of biological and social contagion.
C Castillo-Chavez, DJ Daley, DJ Daley, DJ Watts, DJ Watts, DJ Watts, F Bass, JD Murray, JP Gleeson, L Weng, M Granovetter, MS Granovetter, MS Granovetter, PS Dodds, PS Dodds, PS Dodds, SH Strogatz, TC Schelling, TC Schelling, W Goffman, WO Kermack, WO Kermack, WO Kermack   +22 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Stability of a neural network model with small-world connections

, 2004
Small-world networks are highly clustered networks with small distances among the nodes. There are many biological neural networks that present this kind of connections.
C. Aguirre, C. F. Moukarzel, C. W. Wu, Chunguang Li, D. J. Watts, Guanrong Chen, H. Hong, J. G. White, L. F. Lago-Fernández, M. Barahona, M. E. J. Newman, M. E. J. Newman, M. Joy, P. M. Gade, X. F. Wang, X. Liao   +15 more
core   +1 more source