Results 81 to 90 of about 27,460,944 (326)

The coefficient of determination R2 and intra-class correlation coefficient from generalized linear mixed-effects models revisited and expanded

bioRxiv, 2016
The coefficient of determination R2 quantifies the proportion of variance explained by a statistical model and is an important summary statistic of biological interest.
S Nakagawa, P. C. Johnson, H. Schielzeth
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Automated face recognition using deep neural networks produces robust primate social networks and sociality measures

Methods in Ecology and Evolution, 2023
Longitudinal video archives of behaviour are crucial for examining how sociality shifts over the lifespan in wild animals. New approaches adopting computer vision technology hold serious potential to capture interactions and associations between ...
Daniel P. Schofield, Gregory F. Albery, Josh A. Firth, Alexander Mielke, Misato Hayashi, Tetsuro Matsuzawa, Dora Biro, Susana Carvalho   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Correction to: Rapid turnover of life-cycle-related genes in the brown algae

Genome Biology, 2019
Following publication of the original article [1], it was noticed that the author names were published with initials instead of full names. The article [1] has been updated.
Agnieszka P. Lipinska, Martha L. Serrano-Serrano, Alexandre Cormier, Akira F. Peters, Kazuhiro Kogame, J. Mark Cock, Susana M. Coelho   +6 more
doaj   +1 more source

Probabilistic models of biological enzymatic polymerization.

PLoS ONE, 2021
In this study, hierarchies of probabilistic models are evaluated for their ability to characterize the untemplated addition of adenine and uracil to the 3' ends of mitochondrial mRNAs of the human pathogen Trypanosoma brucei, and for their generative ...
Marshall Hampton, Miranda Galey, Clara Smoniewski, Sara L Zimmer   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phenolic-rich lees from Philippine rice wine (tapuy) increases Caenorhabditis elegans lifespan in spite of having low antioxidant activity

Food Production, Processing and Nutrition
Tapuy is an indigenous wine produced in the Philippines. Rice wine fermentation produces a by-product of rice leftover and microbial biomass, collectively called lees, which usually is discarded as a waste product.
Sean Philippe L. Chua, Lesley Dale Umayat, Paul Mark B. Medina   +2 more
doaj   +1 more source

Fermented beetroot modulates gut microbial carbohydrate metabolism in prediabetes and prevents high-fat diet induced hyperglycemia in a prediabetic model

Current Research in Food Science
The global increase in prevalence of (pre-)diabetes demands immediate intervention strategies. In our earlier work, we demonstrated in vitro antidiabetic potential of a fermented beetroot product (PN39).
Eric Banan-Mwine Daliri, Ashwinipriyadarshini Megur, Jonas Mingaila, Akshay Kumar Vijaya, Toma Balnionytė, Debalina Sakar, Yaiza Carnicero-Mayo, Volker Behrends, Adele Costabile, Aurelijus Burokas   +9 more
doaj   +1 more source

Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model

Nature Communications, 2022
Mutations that enhance the activity of protein kinase C alpha (PKCα) are associated with Alzheimer’s Disease. Here, the authors report that the enhanced activity of one variant, PKCα M489V, is sufficient to rewire the brain phosphoproteome, drive ...
Gema Lordén, Jacob M. Wozniak, Kim Doré, Lara E. Dozier, Chelsea Cates-Gatto, Gentry N. Patrick, David J. Gonzalez, Amanda J. Roberts, Rudolph E. Tanzi, Alexandra C. Newton   +9 more
doaj   +1 more source