Results 31 to 40 of about 2,634,573 (271)

Regional and aging-specific cellular architecture of non-human primate brains

open access: yesGenome Medicine
Background Deciphering the functionality and dynamics of brain networks across different regions and age groups in non-human primates (NHPs) is crucial for understanding the evolution of human cognition as well as the processes underlying brain ...
Yun-Mei Wang   +15 more
doaj   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein   +3 more
wiley   +1 more source

DNA replication fork speed acts as a pacer in cortical neurogenesis

open access: yesNature Communications
DNA replication fork speed, which controls the rate of genome duplication, has emerged as a key regulator of cellular plasticity. However, its role in neurogenesis remains unexplored.
Jianhong Wang   +6 more
doaj   +1 more source

Nonlinear Models of Neural and Genetic Network Dynamics:\ud \ud Natural Transformations of Łukasiewicz Logic LM-Algebras in a Łukasiewicz-Topos as Representations of Neural Network Development and Neoplastic Transformations \ud [PDF]

open access: yes, 2011
A categorical and Łukasiewicz-Topos framework for Algebraic Logic models of nonlinear dynamics in complex functional systems such as Neural Networks, Cell Genome and Interactome Networks is introduced.
Baianu, Professor I.C.
core  

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

Chromosome-level genome of Cyprinus rubrofuscus ♀ × Sinocyclocheilus grahami ♂ provides high-quality parental haplotype genomes and insights into hybrid economic traits enhancement

open access: yesBMC Genomics
Cyprinids, the largest and most economically significant family of teleosts, comprise over 600 polyploid species, whose genomic complexity presents challenges in deciphering the genetic basis of phenotypic diversity.
Yanhui Yin   +7 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine   +10 more
wiley   +1 more source

Object-translocation induces event coding in the rat hippocampus

open access: yesCommunications Biology
Episodic memory is the ability to recall personally experienced events that are situated within specific spatial contexts. Within a navigation environment, salient objects can function as landmarks, and interactions with them can be encoded as distinct ...
Ya-Li Duan   +9 more
doaj   +1 more source

Targeting cuproptosis by zinc pyrithione in triple-negative breast cancer

open access: yesiScience, 2023
Summary: Triple-negative breast cancer (TNBC) poses a considerable challenge due to its aggressive nature. Notably, metal ion-induced cell death, such as ferroptosis, has garnered significant attention and demonstrated potential implications for cancer ...
Xu Yang   +9 more
doaj   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga   +56 more
wiley   +1 more source

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