Results 41 to 50 of about 25,628,644 (319)
Purification of Long Non-coding RNAs on Replication Forks Using iROND (Isolate RNAs on Nascent DNA)
Bio-Protocol, 2023 Fork stability is key to genome DNA duplication and genetic integrity. Long non-coding RNAs (LncRNAs) may play vital roles in fork stabilization and chromatin remodeling.
Weidao Zhang +4 more
doaj +1 more source
Determination of Nonlinear Genetic Architecture using Compressed Sensing
, 2015 We introduce a statistical method that can reconstruct nonlinear genetic models (i.e., including epistasis, or gene-gene interactions) from phenotype-genotype (GWAS) data.
Ho, Chiu Man, Hsu, Stephen D. H.
core +1 more source
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
Nature, 2014 Next-generation sequencing of human tumours has refined our understanding of the mutational processes operative in cancer initiation and progression, yet major questions remain regarding the factors that induce driver mutations and the processes that ...
Peter M. K. Westcott +13 more
semanticscholar +1 more source
Fused in sarcoma (FUS) inhibits milk production efficiency in mammals
Nature CommunicationsEfficient milk production in mammals confers evolutionary advantages by facilitating the transmission of energy from mother to offspring. However, the regulatory mechanism responsible for the gradual establishment of milk production efficiency in mammals,
Haili Shao +15 more
doaj +1 more source
Geographic variation in walking activity in the red flour beetle Tribolium castaneum
Population Ecology, EarlyView.This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley +1 more source
Disease Models & Mechanisms, 2020 Induced pluripotent stem cell (iPSC) technologies have provided in vitro models of inaccessible human cell types, yielding new insights into disease mechanisms especially for neurological disorders.
Viola Volpato, C. Webber
semanticscholar +1 more source
Single-cell expression profiling of bat wing development
Nature CommunicationsBats are the only true-flight mammals, with wings formed by elongated digits and wing membranes. Despite the uniqueness, the cellular and molecular aspects of bat wing development remain largely unknown. Here, we use single-cell transcriptomic sequencing
Xue Lyu +7 more
doaj +1 more source
Population Ecology, EarlyView.We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva +6 more
wiley +1 more source
Graphical Models for Genetic Analyses
Statistical Science, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lauritzen, S.L., Sheehan, Nuala A.
openaire +7 more sources
Regional and aging-specific cellular architecture of non-human primate brains
Genome MedicineBackground Deciphering the functionality and dynamics of brain networks across different regions and age groups in non-human primates (NHPs) is crucial for understanding the evolution of human cognition as well as the processes underlying brain ...
Yun-Mei Wang +15 more
doaj +1 more source