Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken+13 more
core +10 more sources
Background and Objectives: The knowledge that the cholinergic neurons from pedunculopontine nucleus (PPN) are vulnerable to the degeneration in early stages of the Parkinson disease progression has opened new perspectives to the development of ...
Lisette Blanco-Lezcano+9 more
doaj +1 more source
Clinical reasoning in feline epilepsy: Which combination of clinical information is useful? [PDF]
We sought to identify the association between clinical risk factors and the diagnosis of idiopathic epilepsy (IE) or structural epilepsy (SE) in cats, using statistical models to identify combinations of discrete parameters from the patient signalment ...
Packer, R M A+4 more
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CHANGING PERSPECTIVE ON PERCEPTION PHYSIOLOGY: CAN YOU REALLY SEE WHAT IS HAPPENING?
Perception is a complex, neural mechanism that requires organization and interpretation of input meaning and it has been a key topic in medicine, neuroscience and philosophy for centuries.
Giuseppe Giglia
doaj +1 more source
Serum Cytokines Predict Neurological Damage in Genetically Diverse Mouse Models
Viral infections contribute to neurological and immunological dysfunction driven by complex genetic networks. Theiler’s murine encephalomyelitis virus (TMEV) causes neurological dysfunction in mice and can model human outcomes to viral infections.
Aracely A. Pérez Gómez+8 more
doaj +1 more source
Modulation of adult-born neurons in the inflamed hippocampus. [PDF]
Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
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Current Animal Models of Postoperative Spine Infection and Potential Future Advances. [PDF]
Implant related infection following spine surgery is a devastating complication for patients and can potentially lead to significant neurological compromise, disability, morbidity, and even mortality.
Bernthal, NM+7 more
core +1 more source
Incorporating neurological and behavioral mechanisms of sociality into predator-prey models
Consumer-resource population models drive progress in predicting and understanding predation. However, they are often built by averaging the foraging outcomes of individuals to estimate per capita functional responses (functions that describe predation ...
James L. L. Lichtenstein+2 more
doaj +1 more source
Automated Measurement of Adherence to Traumatic Brain Injury (TBI) Guidelines using Neurological ICU Data [PDF]
Using a combination of physiological and treatment information from neurological ICU data-sets, adherence to traumatic brain injury (TBI) guidelines on hypotension, intracranial pressure (ICP) and cerebral perfusion pressure (CPP) is calculated ...
Moss, Laura, Piper, Ian, Stell, Anthony
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Bilirubin-Induced Neurological Damage: Current and Emerging iPSC-Derived Brain Organoid Models
Bilirubin-induced neurological damage (BIND) has been a subject of studies for decades, yet the molecular mechanisms at the core of this damage remain largely unknown.
Abida Islam Pranty+2 more
doaj +1 more source