Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
, 2013 Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken +13 more
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Brain Organoids: Filling the Need for a Human Model of Neurological Disorder
Biology, 2021 Neurological disorders are among the leading causes of death worldwide, accounting for almost all onsets of dementia in the elderly, and are known to negatively affect motor ability, mental and cognitive performance, as well as overall wellbeing and ...
Philip Jalink, Massimiliano Caiazzo
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Neuroimaging in Functional Movement Disorders. [PDF]
, 2019 PURPOSE OF REVIEW: Functional movement disorders are common and disabling causes of abnormal movement control. Here, we review the current state of the evidence on the use of neuroimaging in Functional movement disorders, particularly its role in helping
Edwards, MJ, Roelofs, JJ, Teodoro, T
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Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery. [PDF]
, 2020 Background Impaired neurological function affects 85% to 90% of cardiac arrest (CA) survivors. Pulsatile blood flow may play an important role in neurological recovery after CA.
Akbari, Yama +6 more
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Acute hydrogen sulfide-induced neuropathology and neurological sequelae: challenges for translational neuroprotective research. [PDF]
, 2016 Hydrogen sulfide (H2 S), the gas with the odor of rotten eggs, was formally discovered in 1777, over 239 years ago. For many years, it was considered an environmental pollutant and a health concern only in occupational settings. Recently, however, it was
Anantharam, Poojya +4 more
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Validation in Drosophila of the in silico predicted clomipramine as repurposable for SOD1-ALS
NeurotherapeuticsAmyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by progressive motor neuron degeneration and muscle weakness, generally leading to death due to respiratory failure within 2–5 years of symptom onset.
Francesco Liguori +7 more
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Role of the Calcium Plateau in the Neuronal Injury and Behavioral Morbidities Following Organophosphate Intoxication [PDF]
, 2016 Organophosphate (OP) chemicals include nerve agents and pesticides, and there is a growing concern of OP based chemical attacks against civilians. Current antidotes are essential in limiting immediate mortality associated with OP exposure.
Battaglia F.P. +8 more
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Automated Measurement of Adherence to Traumatic Brain Injury (TBI) Guidelines using Neurological ICU Data [PDF]
, 2018 Using a combination of physiological and treatment information from neurological ICU data-sets, adherence to traumatic brain injury (TBI) guidelines on hypotension, intracranial pressure (ICP) and cerebral perfusion pressure (CPP) is calculated ...
Moss, Laura, Piper, Ian, Stell, Anthony
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Brain Age from the Electroencephalogram of Sleep [PDF]
, 2018 The human electroencephalogram (EEG) of sleep undergoes profound changes with age. These changes can be conceptualized as "brain age", which can be compared to an age norm to reflect the deviation from normal aging process.
Akeju, Oluwaseun +10 more
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Experimental Animal Models in Neurological Diseases
Düzce Tıp Fakültesi DergisiThe human brain is a structure that controls billions of neurons and trillions of connections. Having a unique anatomy with countless neurons and connections makes its understanding even more complex.
Neslihan Şirin, Şerif Demir
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