Assessing Drug Administration Techniques in Zebrafish Models of Neurological Disease [PDF]
Neurological diseases, including neurodegenerative and neurodevelopmental disorders, affect nearly one in six of the world’s population. The burden of the resulting deaths and disability is set to rise during the next few decades as a consequence ...
Chaoul, Victoria +13 more
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Genetically engineered pig models of neurological diseases [PDF]
Genetically modified animal models are commonly used for in vivo studies of human diseases. Mice are the most common animal models used in biomedical research, which have provided important insights into disease pathogenesis and are widely used to find ...
Li, Jun +4 more
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Recent advances in biofabricated gut models to understand the gut-brain axis in neurological diseases [PDF]
Increasing evidence has accumulated that gut microbiome dysbiosis could be linked to neurological diseases, including both neurodegenerative and psychiatric diseases. With the high prevalence of neurological diseases, there is an urgent need to elucidate
Han, Hohyeon, Jang, Jinah
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Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders [PDF]
Positron emission tomography (PET) provides dynamic images of the biodistribution of radioactive tracers in the brain. Through application of the principles of compartmental analysis, tracer uptake can be quantified in terms of specific physiological ...
Jupp, Bianca +8 more
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Addressing New Therapeutic Strategies Using Models [PDF]
A disease model displays pathological processes observed in human or animal diseases. The models are fundamental tools in biomedical research, and they are invaluable for providing new insights into mechanisms underlying organ function, establishing the ...
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Serum Cytokines Predict Neurological Damage in Genetically Diverse Mouse Models
Viral infections contribute to neurological and immunological dysfunction driven by complex genetic networks. Theiler’s murine encephalomyelitis virus (TMEV) causes neurological dysfunction in mice and can model human outcomes to viral infections.
Aracely A. Pérez Gómez +8 more
doaj +1 more source
Animal and cell models for Lesch-Nyhan syndrome [PDF]
Lesch–Nyhan Disease (LND) is a rare X-linked recessive metabolic and neurological syndrome due to the deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT).
Santucci A. +3 more
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Cerebral Organoids as Models for Neurological Disorders [PDF]
Despite the devastating effects of neurological disorders on millions of people each year, for decades, brain research remained stagnant in the face of scientific advancement in other areas.
Esther Karman
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Comparison of different speech tasks among adults who stutter and adults who do not stutter
OBJECTIVES: In this study, we compared the performance of both fluent speakers and people who stutter in three different speaking situations: monologue speech, oral reading and choral reading. This study follows the assumption that the neuromotor control
Ana Paula Ritto +3 more
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Incorporating neurological and behavioral mechanisms of sociality into predator-prey models
Consumer-resource population models drive progress in predicting and understanding predation. However, they are often built by averaging the foraging outcomes of individuals to estimate per capita functional responses (functions that describe predation ...
James L. L. Lichtenstein +2 more
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