Results 21 to 30 of about 518,429 (303)
Neurological Phenotypes in Mouse Models of Mitochondrial Disease and Relevance to Human Neuropathology [PDF]
, 2023 Mitochondrial diseases represent the most common inherited neurometabolic disorders, for which no effective therapy currently exists for most patients. The unmet clinical need requires a more comprehensive understanding of the disease mechanisms and the ...
Elizaveta A. Olkhova +5 more
core +2 more sources
Developing and validating a predictive model for stroke progression [PDF]
, 2011 <p><b>Background:</b> Progression is believed to be a common and important complication in acute stroke, and has been associated with increased mortality and morbidity.
O. Wu +9 more
core +1 more source
Early Treatment with Metformin Improves Neurological Outcomes in Lafora Disease
, 2022 Lafora disease is a fatal form of progressive myoclonic epilepsy caused by mutations in the EPM2A or NHLRC1/EPM2B genes that usually appears during adolescence.
María Machío-Castello +20 more
core +1 more source
Cerebellar dysfunction in rodent models with dystonia, tremor, and ataxia
Dystonia, 2023 Dystonia is a movement disorder characterized by involuntary co- or over-contractions of the muscles, which results in abnormal postures and movements. These symptoms arise from the pathophysiology of a brain-wide dystonia network.
Meike E. van der Heijden +6 more
doaj +1 more source
Medicina, 2019 Background and Objectives: The knowledge that the cholinergic neurons from pedunculopontine nucleus (PPN) are vulnerable to the degeneration in early stages of the Parkinson disease progression has opened new perspectives to the development of ...
Lisette Blanco-Lezcano +9 more
doaj +1 more source
Zebrafish as a Model for Neurological Disorders
International Journal of Molecular Sciences, 2022 Over the past two decades, the simplicity and the versatility of the zebrafish (Danio rerio) have helped make it one of the main animal models used to address an increasing number of issues, from fundamental research to clinical investigations, drug discovery [...]
openaire +3 more sources
CHANGING PERSPECTIVE ON PERCEPTION PHYSIOLOGY: CAN YOU REALLY SEE WHAT IS HAPPENING?
Euromediterranean Biomedical Journal, 2018 Perception is a complex, neural mechanism that requires organization and interpretation of input meaning and it has been a key topic in medicine, neuroscience and philosophy for centuries.
Giuseppe Giglia
doaj +1 more source
Influence of data sampling methods on the representation of neural spiking activity in vivo
iScience, 2022 Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden +2 more
doaj +1 more source
, 2023 During an emergency rescue operation, rescuers have to deal with many different health complications like cardiovascular, respiratory, neurological, psychiatric, etc.
Aniebiet Micheal Ezekiel +2 more
core +1 more source
Assessing Drug Administration Techniques in Zebrafish Models of Neurological Disease [PDF]
, 2023 Neurological diseases, including neurodegenerative and neurodevelopmental disorders, affect nearly one in six of the world’s population. The burden of the resulting deaths and disability is set to rise during the next few decades as a consequence ...
Chaoul, Victoria +13 more
core +1 more source