In Vitro Blood–Brain Barrier-Integrated Neurological Disorder Models Using a Microfluidic Device [PDF]
Micromachines, 2019 The blood−brain barrier (BBB) plays critical role in the human physiological system such as protection of the central nervous system (CNS) from external materials in the blood vessel, including toxicants and drugs for several neurological disorders,
Jin-Ha Choi +2 more
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Non-Mammalian Models for Understanding Neurological Defects in RASopathies [PDF]
BiomedicinesRASopathies, a group of neurodevelopmental congenital disorders stemming from mutations in the RAS/MAPK pathway, present a unique opportunity to delve into the intricacies of complex neurological disorders.
Mario Rodríguez-Martín +5 more
doaj +2 more sources
Early Treatment with Metformin Improves Neurological Outcomes in Lafora Disease [PDF]
, 2022 Lafora disease is a fatal form of progressive myoclonic epilepsy caused by mutations in the EPM2A or NHLRC1/EPM2B genes that usually appears during adolescence.
María Machío-Castello +20 more
core +1 more source
Time-Efficient Identification Procedure for Neurological Complications of Rescue Patients in an Emergency Scenario Using Hardware-Accelerated Artificial Intelligence Models [PDF]
, 2023 During an emergency rescue operation, rescuers have to deal with many different health complications like cardiovascular, respiratory, neurological, psychiatric, etc.
Aniebiet Micheal Ezekiel +2 more
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Neurological Phenotypes in Mouse Models of Mitochondrial Disease and Relevance to Human Neuropathology [PDF]
, 2023 Mitochondrial diseases represent the most common inherited neurometabolic disorders, for which no effective therapy currently exists for most patients. The unmet clinical need requires a more comprehensive understanding of the disease mechanisms and the ...
Elizaveta A. Olkhova +5 more
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Developing and validating a predictive model for stroke progression [PDF]
, 2011 <p><b>Background:</b> Progression is believed to be a common and important complication in acute stroke, and has been associated with increased mortality and morbidity.
O. Wu +9 more
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Handbook of animal models in neurological disorders [PDF]
, 2022 Handbook of Animal Models in Neurological Disorders will better readers’ understanding of a large variety of animal models and their applicability in studying a number of neurological disorders.
Preedy, Victor +2 more
core
Neurological models of cognitive processing [PDF]
, 1989 A framework is proposed from which to evaluate contemporary neurological models of cognitive processing. Selected models are classified as unidimensional, bidimensional, or tridimensional according to the neuraxes that they address.
Willis, W. Grant
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Influence of data sampling methods on the representation of neural spiking activity in vivo
iScience, 2022 Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden +2 more
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Zebrafish as a Model for Neurological Disorders
International Journal of Molecular Sciences, 2022 Over the past two decades, the simplicity and the versatility of the zebrafish (Danio rerio) have helped make it one of the main animal models used to address an increasing number of issues, from fundamental research to clinical investigations, drug discovery [...]
openaire +3 more sources