Results 11 to 20 of about 839,668 (306)

Nurr1, Pitx3, and α7 nAChRs mRNA Expression in Nigral Tissue of Rats with Pedunculopontine Neurotoxic Lesion

open access: yesMedicina, 2019
Background and Objectives: The knowledge that the cholinergic neurons from pedunculopontine nucleus (PPN) are vulnerable to the degeneration in early stages of the Parkinson disease progression has opened new perspectives to the development of ...
Lisette Blanco-Lezcano   +9 more
doaj   +1 more source

CHANGING PERSPECTIVE ON PERCEPTION PHYSIOLOGY: CAN YOU REALLY SEE WHAT IS HAPPENING?

open access: yesEuromediterranean Biomedical Journal, 2018
Perception is a complex, neural mechanism that requires organization and interpretation of input meaning and it has been a key topic in medicine, neuroscience and philosophy for centuries.
Giuseppe Giglia
doaj   +1 more source

Influence of data sampling methods on the representation of neural spiking activity in vivo

open access: yesiScience, 2022
Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden   +2 more
doaj   +1 more source

Modeling neurological disorders using brain organoids

open access: yesSeminars in Cell & Developmental Biology, 2021
Neurological disorders are challenging to study given the complexity and species-specific features of the organ system. Brain organoids are three dimensional structured aggregates of neural tissue that are generated by self-organization and differentiation from pluripotent stem cells under optimized culture conditions.
Daniel Y, Zhang   +2 more
openaire   +3 more sources

Clinical reasoning in feline epilepsy: Which combination of clinical information is useful? [PDF]

open access: yes, 2017
We sought to identify the association between clinical risk factors and the diagnosis of idiopathic epilepsy (IE) or structural epilepsy (SE) in cats, using statistical models to identify combinations of discrete parameters from the patient signalment ...
Packer, R M A   +4 more
core   +2 more sources

Fly model causes neurological rethink

open access: yeseLife, 2013
A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.
Madhumala K, Sadanandappa   +2 more
openaire   +5 more sources

Functional outcome of patients with spinal cord injury: rehabilitation outcome study [PDF]

open access: yes, 1999
Objective: To increase our knowledge of neurological recovery and functional outcome of patients with spinal cord injuries in order to make more successful rehabilitation programmes based on realistic goals.Design: Descriptive analysis of data gathered ...
G A Mulder   +12 more
core   +1 more source

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

open access: yes, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
A Hainard   +44 more
core   +4 more sources

Isoprostanoids in Clinical and Experimental Neurological Disease Models

open access: yesAntioxidants, 2018
Isoprostanoids are a large family of compounds derived from non-enzymatic oxidation of polyunsaturated fatty acids (PUFAs). Unlike other oxidative stress biomarkers, they provide unique information on the precursor of the targeted PUFA.
Cinzia Signorini   +9 more
doaj   +1 more source

Serum Cytokines Predict Neurological Damage in Genetically Diverse Mouse Models

open access: yesCells, 2022
Viral infections contribute to neurological and immunological dysfunction driven by complex genetic networks. Theiler’s murine encephalomyelitis virus (TMEV) causes neurological dysfunction in mice and can model human outcomes to viral infections.
Aracely A. Pérez Gómez   +8 more
doaj   +1 more source

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