Results 21 to 30 of about 777,778 (283)

Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury [PDF]

, 2017
Objective: Exposure to repetitive concussion, or mild traumatic brain injury (mTBI), has been linked with increased risk of long-term neurodegenerative changes, specifically chronic traumatic encephalopathy (CTE).
Acker, Christopher M., Ait-Ghezala, Ghania, Bachmeier, Corbin, Crawford, Fiona, Crynen, Gogce, Davies, Peter, Ferguson, Scott, Mouzon, Benoit C., Mullan, Michael, Ojo, Joseph O., Paris, Daniel, Stewart, William   +11 more
core   +2 more sources

Brain Organoids: Filling the Need for a Human Model of Neurological Disorder

Biology, 2021
Neurological disorders are among the leading causes of death worldwide, accounting for almost all onsets of dementia in the elderly, and are known to negatively affect motor ability, mental and cognitive performance, as well as overall wellbeing and ...
Philip Jalink, Massimiliano Caiazzo
doaj   +1 more source

Comparison of different speech tasks among adults who stutter and adults who do not stutter

Clinics, 2016
OBJECTIVES: In this study, we compared the performance of both fluent speakers and people who stutter in three different speaking situations: monologue speech, oral reading and choral reading. This study follows the assumption that the neuromotor control
Ana Paula Ritto, Julia Biancalana Costa, Fabiola Staróbole Juste, Claudia Regina Furquim de Andrade   +3 more
doaj   +1 more source

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
A Hainard, B Beutler, B Courtioux, B Namangala, CA Hunter, CA Hunter, CF Calvo, EN Benveniste, F Checchi, F Esamai, G Binz, H Reiber, H Reiber, H Reiber, Hansotto Reiber, HY Hassan, J Kabore, J Rodgers, Jeremy M. Sternberg, JM Sternberg, JM Sternberg, JM Sternberg, Joseph Mathu Ndung'u, KW Moore, L Maclean, L MacLean, L MacLean, L MacLean, LJ Morrison, LM MacLean, Lorna MacLean, M Sjogren, MC Okomo-Assoumou, P Cattand, PD Eckersall, Peter G. E. Kennedy, PG Kennedy, PGE Kennedy, PGE Kennedy, TN Baral, V Jamonneau, V Lejon, V Lejon, V Lejon, W Masocha   +44 more
core   +4 more sources

Companion animal models of neurological disease

Journal of Neuroscience Methods, 2020
Clinical translation of novel therapeutics that improve the survival and quality of life of patients with neurological disease remains a challenge, with many investigational drug and device candidates failing in advanced stage clinical trials. Naturally occurring inherited and acquired neurological diseases, such as epilepsy, inborn errors of ...
John H. Rossmeisl, John H. Rossmeisl, Brittanie Partridge   +2 more
openaire   +3 more sources

Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review [PDF]

, 2009
Background Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke.
Alvarez-Dolado, Bath, Bath, Claire L. Gibson, Crain, Crossley, del Zoppo, Egger, England, Fisher, Gibson, Gibson, Gibson, Han, Hasselblatt, Hermann, Jendelova, Kawada, Kollmar, Komine-Kobayashi, Lan, Lee, Lees, Macleod, Matchett, Minnerup, Nagata, Philip M.W. Bath, Schabitz, Schneider, Schneider, Sehara, Sehara, Sena, Sevimli, Shuaib, Shyu, Shyu, Shyu, Six, Solaroglu, Solaroglu, Sprigg, Sprigg, Sykova, Taguchi, Timothy J. England, Toth, Vellenga, Wardlaw, Willmot, Yanqing, Zhao, Zhao, Zsebo, Zucali   +55 more
core   +2 more sources

Current animal models of extracorporeal cardiopulmonary resuscitation: A scoping review

Resuscitation Plus, 2023
Aim: Animal models of Extracorporeal Cardiopulmonary Resuscitation (ECPR) focusing on neurological outcomes are required to further the development of this potentially life-saving technology.
Shinichi Ijuin, Keibun Liu, Denzil Gill, Sun Kyun Ro, Jana Vukovic, Satoshi Ishihara, Jan Belohlavek, Gianluigi Li Bassi, Jacky Y Suen, John F Fraser   +9 more
doaj   +1 more source

Molecular Targets of Cannabidiol in Experimental Models of Neurological Disease

Molecules, 2020
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid known for its beneficial effects including antioxidant and anti-inflammatory properties. Moreover, CBD is a compound with antidepressant, anxiolytic, anticonvulsant and antipsychotic effects ...
Serena Silvestro, Giovanni Schepici, Placido Bramanti, Emanuela Mazzon   +3 more
doaj   +1 more source

Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]

, 2004
Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and ...
Candelario-Jalil, Eduardo, Fiebich, Bernd L., García-Cabrera, Michel, González-Falcón, Armando, León, Olga S.   +4 more
core   +1 more source

Clinical reasoning in canine spinal disease: what combination of clinical information is useful? [PDF]

, 2015
Spinal disease in dogs is commonly encountered in veterinary practice. Numerous diseases may cause similar clinical signs and presenting histories. The study objective was to use statistical models to identify combinations of discrete parameters from the
ABRAMSON, ARMAŞU, AWANO, BAGLEY, BESALTI, BRISSON, DA COSTA, DA COSTA, DA COSTA, DE DECKER, DE RISIO, DE RISIO, DE RISIO, DELAMAIDE GASPER, DRIVER, GANDINI, HOLDER, JEFFERY, JULL, KRANENBURG, LANE, LEVINE, LU, MAY, MCKEE, MEIJ, PALUS, PARENT, PARK, RUSBRIDGE, RUSBRIDGE, SCHMIDT, TABACHNICK, TIPOLD, TIPOLD, VAN WIE, ZENG   +36 more
core   +2 more sources