Results 51 to 60 of about 777,778 (283)

Vitamin B6 deficiency cooperates with oncogenic Ras to induce malignant tumors in Drosophila

Cell Death and Disease
Vitamin B6 is a water-soluble vitamin which possesses antioxidant properties. Its catalytically active form, pyridoxal 5’-phosphate (PLP), is a crucial cofactor for DNA and amino acid metabolism. The inverse correlation between vitamin B6 and cancer risk
Eleonora Pilesi, Giulia Tesoriere, Angelo Ferriero, Elisa Mascolo, Francesco Liguori, Luca Argirò, Chiara Angioli, Angela Tramonti, Roberto Contestabile, Cinzia Volontè, Fiammetta Vernì   +10 more
doaj   +1 more source

Flaviviruses—Induced Neurological Sequelae

Pathogens
Flaviviruses, a group of single-stranded RNA viruses spread by mosquitoes or ticks, include several significant neurotropic viruses, such as West Nile virus (WNV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Zika virus ...
Samantha Gabrielle Cody, Awadalkareem Adam, Andrei Siniavin, Sam S. Kang, Tian Wang   +4 more
doaj   +1 more source

Neurological, Cognitive, and Psychological Findings Among Survivors of Ebola Virus Disease From the 1995 Ebola Outbreak in Kikwit, Democratic Republic of Congo: A Cross-sectional Study. [PDF]

, 2019
BackgroundClinical sequelae of Ebola virus disease (EVD) have not been described more than 3 years postoutbreak. We examined survivors and close contacts from the 1995 Ebola outbreak in Kikwit, Democratic Republic of Congo (DRC), and determined ...
Bjornson, Zach, Bramble, Matthew S, Glymour, M Maria, Hoff, Nicole A, Kelly, J Daniel, McIlwain, David, Mukadi, Patrick, Musene, Kamy, Muyembe-Tamfum, Jean Jacques, Nolan, Garry P, Okitolonda-Wemakoy, Emile, Okitundu, Daniel, Porco, Travis C, Rimoin, Anne W, Rutherford, George W, Spencer, D'Andre   +15 more
core  

A Laser-Guided Spinal Cord Displacement Injury in Adult Mice [PDF]

, 2018
Mouse models are unique for studying molecular mechanisms of neurotrauma because of the availability of various genetic modified mouse lines. For spinal cord injury (SCI) research, producing an accurate injury is essential, but it is challenging because ...
Bakare, Adewale A., Fry, Collin M.E., Qu, Wenrui, Shields, Christopher B., Shields, Lisa B.E., Wu, Xiangbing, Xu, Xiao-Ming, Zhang, Yi Ping   +7 more
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Tyrosine Hydroxylase, Vesicular Monoamine Transporter and Dopamine Transporter mRNA Expression in Nigrostriatal Tissue of Rats with Pedunculopontine Neurotoxic Lesion

Behavioral Sciences, 2018
Background: The degeneration of the pedunculopontine nucleus (PPN) precedes the degeneration of the nigral cells in the pre-symptomatic stages of Parkinson’s disease (PD).
Lisette Blanco-Lezcano, Esteban Alberti-Amador, Mei-Li Díaz-Hung, María Elena González-Fraguela, Bárbara Estupiñán-Díaz, Teresa Serrano-Sánchez, Liliana Francis-Turner, Javier Jiménez-Martín, Yamilé Vega-Hurtado, Isabel Fernández-Jiménez   +9 more
doaj   +1 more source

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

Genome Biology, 2021
Background Many neurodegenerative diseases develop only later in life, when cells in the nervous system lose their structure or function. In many forms of neurodegenerative diseases, this late-onset phenomenon remains largely unexplained.
Matan Sorek, Walaa Oweis, Malka Nissim-Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean K. Simmons, Neville E. Sanjana, Xi Shi, Congyi Lu, Jen Q. Pan, Xiaohong Xu, Mahmoud A. Pouladi, Lisa M. Ellerby, Feng Zhang, Joshua Z. Levin, Eran Meshorer   +17 more
doaj   +1 more source

Recent advances in biofabricated gut models to understand the gut-brain axis in neurological diseases

Frontiers in Medical Technology, 2022
Increasing evidence has accumulated that gut microbiome dysbiosis could be linked to neurological diseases, including both neurodegenerative and psychiatric diseases. With the high prevalence of neurological diseases, there is an urgent need to elucidate
Hohyeon Han, Jinah Jang, Jinah Jang, Jinah Jang, Jinah Jang   +4 more
doaj   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor

eLife
The cerebellum contributes to a diverse array of motor conditions, including ataxia, dystonia, and tremor. The neural substrates that encode this diversity are unclear.
Meike E van der Heijden, Amanda M Brown, Dominic J Kizek, Roy V Sillitoe   +3 more
doaj   +1 more source