Results 51 to 60 of about 1,748,144 (308)

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

open access: yesGenome Biology, 2021
Background Many neurodegenerative diseases develop only later in life, when cells in the nervous system lose their structure or function. In many forms of neurodegenerative diseases, this late-onset phenomenon remains largely unexplained.
Matan Sorek   +17 more
doaj   +1 more source

Recent advances in biofabricated gut models to understand the gut-brain axis in neurological diseases

open access: yesFrontiers in Medical Technology, 2022
Increasing evidence has accumulated that gut microbiome dysbiosis could be linked to neurological diseases, including both neurodegenerative and psychiatric diseases. With the high prevalence of neurological diseases, there is an urgent need to elucidate
Hohyeon Han   +4 more
doaj   +1 more source

NeuroLogic A*esque Decoding: Constrained Text Generation with Lookahead Heuristics [PDF]

open access: yesarXiv, 2021
The dominant paradigm for neural text generation is left-to-right decoding from autoregressive language models. Constrained or controllable generation under complex lexical constraints, however, requires foresight to plan ahead feasible future paths. Drawing inspiration from the A* search algorithm, we propose NeuroLogic A*esque, a decoding algorithm
arxiv  

Flaviviruses—Induced Neurological Sequelae

open access: yesPathogens
Flaviviruses, a group of single-stranded RNA viruses spread by mosquitoes or ticks, include several significant neurotropic viruses, such as West Nile virus (WNV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Zika virus ...
Samantha Gabrielle Cody   +4 more
doaj   +1 more source

Influence of data sampling methods on the representation of neural spiking activity in vivo

open access: yesiScience, 2022
Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden   +2 more
doaj  

Automated Measurement of Adherence to Traumatic Brain Injury (TBI) Guidelines using Neurological ICU Data [PDF]

open access: yes, 2018
Using a combination of physiological and treatment information from neurological ICU data-sets, adherence to traumatic brain injury (TBI) guidelines on hypotension, intracranial pressure (ICP) and cerebral perfusion pressure (CPP) is calculated ...
Moss, Laura, Piper, Ian, Stell, Anthony
core   +1 more source

Vitamin B6 deficiency cooperates with oncogenic Ras to induce malignant tumors in Drosophila

open access: yesCell Death and Disease
Vitamin B6 is a water-soluble vitamin which possesses antioxidant properties. Its catalytically active form, pyridoxal 5’-phosphate (PLP), is a crucial cofactor for DNA and amino acid metabolism. The inverse correlation between vitamin B6 and cancer risk
Eleonora Pilesi   +10 more
doaj   +1 more source

Machine learning-based predictor for neurologic outcomes in patients undergoing extracorporeal cardiopulmonary resuscitation

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundWe investigated the predictors of poor neurological outcomes in extracorporeal cardiopulmonary resuscitation (ECPR) patients using machine learning (ML) approaches.MethodsThis study was a retrospective, single-center, observational study that ...
Tae Wan Kim   +3 more
doaj   +1 more source

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]

open access: yes, 2014
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M   +5 more
core   +2 more sources

Tyrosine Hydroxylase, Vesicular Monoamine Transporter and Dopamine Transporter mRNA Expression in Nigrostriatal Tissue of Rats with Pedunculopontine Neurotoxic Lesion

open access: yesBehavioral Sciences, 2018
Background: The degeneration of the pedunculopontine nucleus (PPN) precedes the degeneration of the nigral cells in the pre-symptomatic stages of Parkinson’s disease (PD).
Lisette Blanco-Lezcano   +9 more
doaj   +1 more source

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