Results 71 to 80 of about 7,462,898 (307)

Stem cell transplantation in neurological diseases: improving effectiveness in animal models.

Frontiers in Cell and Developmental Biology, 2014
Neurological diseases afflict a growing proportion of the human population. There are two reasons for this: first, the average age of the population (especially in the industrialised world) is increasing, and second, the diagnostic tools to detect these ...
Raffaella eAdami, Giuseppe eScesa, Daniele eBottai   +2 more
doaj   +1 more source

Modeling the Neurologic and Cognitive Effects of Hyponatremia [PDF]

Journal of the American Society of Nephrology, 2016
Acute hyponatremia causes swelling of brain cells and, if of a sufficient degree, increased intracranial pressure. This is a consequence of the relative impermeability of the blood-brain barrier to sodium ions[1][1]; this principle underlies the clinical utility of hypertonic NaCl infusion in ...
openaire   +2 more sources

“Shake-Shake”: A new neurological syndrome or a functional neurological disorder? [PDF]

Neuropsychiatric disorders are common neurological presentations that can pose a major diagnostic challenge in general medical practice. Functional neurological disorder presents with medical symptoms that can easily remain unrecognised or get ...
Cathy Abbo, Emmanuel Mpamizo, Emmanuel Musana, Neil Scolding   +3 more
core   +1 more source

Acute neurological disease as a trigger or co-occurrence of transient global amnesia: a case series and systematic review.

, 2022
Transient global amnesia (TGA) represents a benign neurological syndrome of unknown pathophysiology, often accompanied by vanishing hippocampal punctate lesions on diffusion-weighted imaging (hippocampal punctate diffusion lesion, HPDL).
Nannoni, S., Piffer, S., Beaud, V., Maeder, P., Rouaud, O., Cereda, C.W., Michel, P., Maulucci, F.   +7 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

Frontiers in Pharmacology
BackgroundNeurological diseases such as stroke and Alzheimer’s disease pose increasing challenges to global public health. Salvianolic Acid B (SalB), a major active component of Salvia miltiorrhiza, has garnered attention due to its anti-inflammatory ...
Shijun Bi, Shibing Liu, Kunyuan Zhu, Dandan Gao, Ligang Chen, Chunyong Yu, Guobiao Liang   +6 more
doaj   +1 more source

Building Models of Neurological Language

CoRR
21 pages, 6 ...
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Standards of care for people with disabling (progressive and static) neurological conditions in the hospital and community: standards of care for people with disabling progressive and static neurological conditions in the hospital and community.

, 2001
Neurological conditions are common, affecting over 500,000 people in the Irish population. Recent advances in the neurosciences have improved the outlook many conditions, as major breakthroughs have been achieved. Standing pathogenesis, the prospect of
Neurological Alliance of Ireland
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source