Results 81 to 90 of about 7,767,658 (304)

Exploiting fly models to investigate rare human neurological disorders

Neural Regeneration Research
Rare neurological diseases, while individually are rare, collectively impact millions globally, leading to diverse and often severe neurological symptoms.
Tomomi Tanaka, Hyung-Lok Chung
doaj   +1 more source

Standards of care for people with disabling neurological conditions where cognitive decline is a major feature.

, 2002
This is the third volume of a trilogy outlining the best practice for the care of people with neurological conditions. Volumes I and II dealt with the physically disabling and non-physically disabling neurological conditions respectively.
Elan, Neurological Alliance of Ireland
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Modeling the Neurologic and Cognitive Effects of Hyponatremia [PDF]

Journal of the American Society of Nephrology, 2016
Acute hyponatremia causes swelling of brain cells and, if of a sufficient degree, increased intracranial pressure. This is a consequence of the relative impermeability of the blood-brain barrier to sodium ions[1][1]; this principle underlies the clinical utility of hypertonic NaCl infusion in ...
openaire   +2 more sources

Standards of care for people with disabling (progressive and static) neurological conditions in the hospital and community: standards of care for people with disabling progressive and static neurological conditions in the hospital and community.

, 2001
Neurological conditions are common, affecting over 500,000 people in the Irish population. Recent advances in the neurosciences have improved the outlook many conditions, as major breakthroughs have been achieved. Standing pathogenesis, the prospect of
Neurological Alliance of Ireland
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Building Models of Neurological Language

CoRR
21 pages, 6 ...
openaire   +3 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

Frontiers in Pharmacology
BackgroundNeurological diseases such as stroke and Alzheimer’s disease pose increasing challenges to global public health. Salvianolic Acid B (SalB), a major active component of Salvia miltiorrhiza, has garnered attention due to its anti-inflammatory ...
Shijun Bi, Shibing Liu, Kunyuan Zhu, Dandan Gao, Ligang Chen, Chunyong Yu, Guobiao Liang   +6 more
doaj   +1 more source

Stem cell transplantation in neurological diseases: improving effectiveness in animal models.

Frontiers in Cell and Developmental Biology, 2014
Neurological diseases afflict a growing proportion of the human population. There are two reasons for this: first, the average age of the population (especially in the industrialised world) is increasing, and second, the diagnostic tools to detect these ...
Raffaella eAdami, Giuseppe eScesa, Daniele eBottai   +2 more
doaj   +1 more source