Results 91 to 100 of about 1,820,346 (284)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
NANOSTRUCTURAL PROCESSES OF MELTING AND MOULDING OF THE EUTECTIC SILUMIN
Литьë и металлургия, 2016 It is shown that melting and molding of the eutectic silumin are difficult physical and chemical nanostructural processes. In them the major role is played by the centers of crystallization of the eutectic dendrites of aluminum, aluminum nanocrystals ...
V. Yu. Stetsenko
doaj
Improved design of electrophoretic equipment for rapid sickle-cell-anemia screening [PDF]
, 1974 Effective mass screening may be accomplished by modifying existing electrophoretic equipment in conjunction with multisample applicator used with cellulose-acetate-matrix test paper.
Hirsch, I., Reddick, J. M.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MAIN PROBLEMS OF MOULDING OF SILUMINS. WAYS OF SOLUTION
Литьë и металлургия, 2016 The main problems of silumin’ moulding are connected with insufficient modifying of casting structure, their considerable inclination to gas porosity, difficult to remove nonmetallic inclusions and these features are shown in the article.
E. I. Marukovich, V. Yu. Stetsenko
doaj
Modifying Gravity at Low Redshift
, 2009 We consider the growth of cosmological perturbations in modified gravity models where a scalar field mediates a non-universal Yukawa force between different matter species.
Brax, Philippe +3 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
NANOSTRUCTURAL PROCESSES OF MELTING AND MOULDING OF STEEL
Литьë и металлургия, 2016 It is shown that melting and molding of steel are difficult physical and chemical nanostructural processes. In them the major role is played by the centers of crystallization of dendrites of austenite, austenite nanocrystals, the dissolved and adsorbed ...
V. Yu. Stetsenko
doaj
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source