Results 21 to 30 of about 315,729 (282)

Cells Best Paper Award 2015 Alexander E.

open access: yesCells, 2015
Cells has instituted a “Best Paper” award to recognize the most outstanding papers in the area of cell biology, molecular biology, and biophysics, published in Cells.
Alexander E. Kalyuzhny
doaj   +1 more source

TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. [PDF]

open access: yes, 2015
The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Corbett, Kevin D   +5 more
core   +2 more sources

Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells

open access: yesIET Nanobiotechnology, 2021
The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye   +3 more
doaj   +1 more source

A physical model of cell metabolism [PDF]

open access: yes, 2018
Cell metabolism is characterized by three fundamental energy demands: to sustain cell maintenance, to trigger aerobic fermentation and to achieve maximum metabolic rate.
Fernandez-de-Cossio-Diaz, Jorge   +1 more
core   +2 more sources

Structure of catalase determined by MicroED. [PDF]

open access: yes, 2014
MicroED is a recently developed method that uses electron diffraction for structure determination from very small three-dimensional crystals of biological material.
Gonen, Tamir   +4 more
core   +1 more source

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. [PDF]

open access: yes, 2020
The AAA protein Msp1 extracts mislocalized tail-anchored membrane proteins and targets them for degradation, thus maintaining proper cell organization.
Myasnikov, Alexander   +3 more
core   +3 more sources

Biophysical and flavonoid-binding studies of the G protein ectodomain of group A human respiratory syncytial virus

open access: yesHeliyon, 2019
The human Respiratory Syncytial Virus (hRSV) is the major causative agent of lower respiratory tract diseases in infants, young children and elderly. The membrane protein G is embedded in the viral lipid envelope and plays an adhesion function of the ...
Vitor Brassolatti Machado   +7 more
doaj   +1 more source

Protein cages as building blocks for superstructures

open access: yesEngineering Biology, 2021
Proteins naturally self‐assemble to function. Protein cages result from the self‐assembly of multiple protein subunits that interact to form hollow symmetrical structures with functions that range from cargo storage to catalysis. Driven by self‐assembly,
Ruoxuan Sun, Sierin Lim
doaj   +1 more source

Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. [PDF]

open access: yes, 2020
Cation-chloride-cotransporters (CCCs) catalyze transport of Cl- with K+ and/or Na+across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function.
Brohawn, Stephen Graf   +2 more
core   +2 more sources

Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity. [PDF]

open access: yes, 2019
TMEM16F is activated by elevated intracellular Ca2+, and functions as a small-conductance ion channel and as a phospholipid scramblase. In contrast to its paralogs, the TMEM16A/B calcium-activated chloride channels, mouse TMEM16F has been reported as a ...
Han, Tina W   +4 more
core   +2 more sources

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