Results 21 to 30 of about 319,701 (282)

Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]

open access: yes, 2017
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and the CAS-Novonordisk Foundation, as well as grants from the ‘1000 talents’ recruitment program, and a ‘Great-wall professorship’ from ...
Jin, Wanzhu   +8 more
core   +2 more sources

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. [PDF]

open access: yes, 2020
The AAA protein Msp1 extracts mislocalized tail-anchored membrane proteins and targets them for degradation, thus maintaining proper cell organization.
Myasnikov, Alexander   +3 more
core   +3 more sources

TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. [PDF]

open access: yes, 2015
The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Corbett, Kevin D   +5 more
core   +2 more sources

Gi/o protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na+/K+ ATPase activation

open access: yesNature Communications, 2022
Gi/o protein-coupled receptors (Gi/o-GPCRs) limit β-cell insulin secretion by decreasing Ca2+ entry; however, the underlying mechanism has not been identified. Here, the authors show that Gi/o-GPCRs hyperpolarize mouse and human β-cell membrane potential
Matthew T. Dickerson   +10 more
doaj   +1 more source

Cells Best Paper Award 2015 Alexander E.

open access: yesCells, 2015
Cells has instituted a “Best Paper” award to recognize the most outstanding papers in the area of cell biology, molecular biology, and biophysics, published in Cells.
Alexander E. Kalyuzhny
doaj   +1 more source

Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells

open access: yesIET Nanobiotechnology, 2021
The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye   +3 more
doaj   +1 more source

Mind-life continuity: a qualitative study of conscious experience [PDF]

open access: yes, 2017
There are two fundamental models to understanding the phenomenon of natural life. One is thecomputational model, which is based on the symbolic thinking paradigm. The other is the biologicalorganism model.
Hipólito, Inês, Martins, J.
core   +1 more source

A physical model of cell metabolism [PDF]

open access: yes, 2018
Cell metabolism is characterized by three fundamental energy demands: to sustain cell maintenance, to trigger aerobic fermentation and to achieve maximum metabolic rate.
Fernandez-de-Cossio-Diaz, Jorge   +1 more
core   +2 more sources

Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. [PDF]

open access: yes, 2020
Cation-chloride-cotransporters (CCCs) catalyze transport of Cl- with K+ and/or Na+across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function.
Brohawn, Stephen Graf   +2 more
core   +2 more sources

Biophysical and flavonoid-binding studies of the G protein ectodomain of group A human respiratory syncytial virus

open access: yesHeliyon, 2019
The human Respiratory Syncytial Virus (hRSV) is the major causative agent of lower respiratory tract diseases in infants, young children and elderly. The membrane protein G is embedded in the viral lipid envelope and plays an adhesion function of the ...
Vitor Brassolatti Machado   +7 more
doaj   +1 more source

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