Results 81 to 90 of about 828,245 (371)

Josephson-current induced conformational switching of a molecular quantum dot [PDF]

Phys. Rev. Lett. 102, 047002 (2009), 2008
We discuss the behavior of a two-level system coupled to a quantum dot contacted by superconducting source/drain electrodes, representing a simple model for the conformational degree of freedom of a molecular dot or a break junction. The Josephson current is shown to induce conformational changes, including a complete reversal.
arxiv   +1 more source

Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE. [PDF]

, 2014
The major facilitator superfamily (MFS) is the largest collection of structurally related membrane proteins that transport a wide array of substrates.
Gonen, Tamir, Iadanza, Matthew G, Park, Min-Sun, Wisedchaisri, Goragot, Zheng, Hongjin   +4 more
core   +3 more sources

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

FEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra, Paul Weiland, Pauline Anka Plitzko, Julia Thiery, Laura Czech, Felix Willmund, Patricia Bedrunka, Gert Bange   +7 more
wiley   +1 more source

Methyl 4-Hydroxy-2,2-Dioxo-1H-2λ⁶,1-Benzothiazine-3-Carboxylate and Its Analogs Modified in the Benzene Moiety of the Molecule as New Analgesics

Scientia Pharmaceutica, 2020
In order to identify new regularities of the “structure−analgesic activity” relationship in the series of 2,1-benzothiazine derivatives, the synthesis of methyl 4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate and a group ...
Igor V. Ukrainets, Lidiya A. Petrushova, Svitlana V. Shishkina, Lyudmila V. Sidorenko, Tatiana V. Alekseeva, Inna I. Torianyk, Alexandra A. Davidenko   +6 more
doaj   +1 more source

Different patterns of supramolecular aggregation in three amides containing N-(benzo[d]thiazolyl) substituents

Acta Crystallographica Section E: Crystallographic Communications, 2021
Crystal structures are reported for three amides containing N-benzo[d]thiazole substituents. In N-(benzo[d]thiazol-6-yl)-3-bromobenzamide, C14H9BrN2OS, where the two ring systems are nearly parallel to one another [dihedral angle = 5.8 (2)°], the ...
Ninganayaka Mahesha, Hemmige S. Yathirajan, Holalagudu A. Nagma Banu, Balakrishna Kalluraya, Sabine Foro, Christopher Glidewell   +5 more
doaj   +1 more source

Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family [PDF]

, 2014
Kinesins are responsible for a wide variety of microtubule-based, ATP-dependent functions. Their motor domain drives these activities but the molecular adaptations that specify these diverse and essential cellular activities are poorly understood.
Goulet, Adeline, Grossmann, S.P., Jung, Y., Major, J., Moores, Carolyn A., Rosenfeld, S.S.   +5 more
core   +2 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Crystal structure and conformational analysis of 2-hydroxy-3-(2-methylprop-1-en-1-yl)naphthalene-1,4-dione

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the structure of the title compound, C14H12O3, the substituent side chain, in which the H atoms of both methyl groups are disordered over six equivalent sites, lies outside of the plane of the naphthalenedione ring.
Sannyele Alcantara Emiliano, Sheyla Welma Duarte Silva, Mariano Alves Pereira, Valeria R.dos Santos Malta, Tatiane Luciano Balliano   +4 more
doaj   +1 more source

$\alpha$- and $\beta$- Relaxation Dynamics of a fragile plastic crystal

, 2006
We present a thorough dielectric investigation of the relaxation dynamics of plastic crystalline Freon112, which exhibits freezing of the orientational degrees of freedom into a glassy crystal below 90 K. Among other plastic crystals, Freon112 stands out
Loidl, A., Lunkenheimer, P., Pardo, L. C.   +2 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source