Results 51 to 60 of about 1,119,993 (215)

Development of metachronous rectal cancers in a young man with dyskeratosis congenita: a case report

Journal of Medical Case Reports, 2019
Background DKC1 (dyskerin pseudouridine synthase 1) is a causative gene for X-linked dyskeratosis congenita. Approximately 8% of patients with dyskeratosis congenita have malignancy, but information about the development of malignancy in patients with ...
Motoko Watanabe, Gou Yamamoto, Kenji Fujiyoshi, Yoshito Akagi, Miho Kakuta, Yoji Nishimura, Kiwamu Akagi   +6 more
doaj   +1 more source

Male papillomavirus infection and genotyping in the Qingyuan area

Virology Journal, 2020
Background This study aims to screen the male human papillomavirus (HPV) infection status and genotyping in Qingcheng District, Qingyuan City, Guangdong Province, China to provide a reference basis for formulating prevention strategies for HPV infection.
Wei-Guo Yin, Meng Yang, Lei Peng, Yan-Mei Liu, Bin Cheng, Shu-Xia Xuan, Chen Chen, Feng-Jun Tan   +7 more
doaj   +1 more source

Molecular Diagnosis of Burkitt's Lymphoma

New England Journal of Medicine, 2006
The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma.Tumor-biopsy specimens from 303 patients with aggressive lymphomas were ...
Dave, Sandeep S., Fu, Kai, Wright, George W., Lam, Lloyd T., Kluin, Philip, Boerma, Evert-Jan, Greiner, Timothy, Weisenburger, Dennis D., Rosenwald, Andreas, Ott, German, Müller-Hermelink, Hans-Konrad, Gascoyne, Randy D., Delabie, Jan, Rimsza, Lisa M., Braziel, Rita M., Grogan, Thomas M., Campo, Elias, Jaffe, Elaine S., Dave, Bhavana J., Sanger, Warren, Bast, M, Vose, Julie M., Armitage, James O., Connors, Joseph M., Smeland, Erlend B., Kvaloy, Stein, Holte, Harald, Fisher, Richard I., Miller, Thomas P., Montserrat, Emilio, Wilson, Wyndham H., Bahl, Manisha, Zhao, Hong, Yang, Liming, Powell, John, Simon, Richard, Chan, Wing C., Staudt, Louis M.   +37 more
openaire   +5 more sources

Molecular neuropathology of gliomas

, 2009
Gliomas are the most common primary human brain tumors. They comprise a heterogeneous group of benign and malignant neoplasms that are histologically classified according to the World Health Organization (WHO) classification of tumors of the nervous ...
Markus Riemenschneider, Riemenschneider, Markus J., Reifenberger, Guido, Guido Reifenberger   +3 more
core   +1 more source

Pan-cancer association of a mitochondrial function score with genomic alterations and clinical outcome

Scientific Reports
Mitochondria are pivotal in cellular energy metabolism and have garnered significant attention for their roles in cancer progression and therapy resistance.
Shikun Zhu, Chen Chen, Min Wang, Yue Liu, Baolin Li, Xing Qi, Miao Song, Xuexue Liu, Jia Feng, Jinbo Liu   +9 more
doaj   +1 more source

The Interleukin-1 (IL-1) Superfamily Cytokines and Their Single Nucleotide Polymorphisms (SNPs)

Journal of Immunology Research, 2022
Interleukins (ILs)—which are important members of cytokines—consist of a vast group of molecules, including a wide range of immune mediators that contribute to the immunological responses of many cells and tissues.
Payam Behzadi, Aga Syed Sameer, Saniya Nissar, Mujeeb Zafar Banday, Márió Gajdács, Herney Andrés García-Perdomo, Kulsum Akhtar, Marina Pinheiro, Peter Magnusson, Meysam Sarshar, Cecilia Ambrosi   +10 more
doaj   +1 more source

International Society for Prenatal Diagnosis 2024 Debate 3—Cytogenetics Is a Dinosaur and Should Be Replaced by Molecular Technologies

Cytogenetic technologies such as G-banding chromosome and FISH analyses have long been the gold standard diagnostic test in prenatal genetic testing. However, unbiased next-generation sequencing technologies such as fetal exome or genome sequencing (ES ...
Akkari, Yassmine M. N., Breman, Amy M., Talkowski, Michael E.   +2 more
core   +1 more source

Whole genome amplification for PGD and PND; molecular and a-CGH diagnosis

, 2009
Whole genome amplification amplifies the entire genome in a few hours from samples of minimal DNA quantities, even from single cells. This may have many applications, especially in prenatal diagnosis, PGD and PGS. The hypothesis for chapter 3 was: Can
Glentis, S.
core  

Multilayer analysis of ethnically diverse blood and urine biomarkers for breast cancer risk and prognosis

Scientific Reports
Breast cancer (BC) is one of the most common malignancies among women globally, characterized by complex pathogenesis involving various biomarkers present in blood and urine.
Jia Feng, Xing Qi, Chen Chen, Baolin Li, Min Wang, Xuelong Xie, Kailan Yang, Xuan Liu, Rui min Chen, Tongtong Guo, Jinbo Liu   +10 more
doaj   +1 more source

Immunomodulatory therapy for sepsis: from pathophysiological mechanisms to precision treatment

Frontiers in Cellular and Infection Microbiology
Sepsis is a life-threatening syndrome marked by immune dysregulation, progressing from hyperinflammation to immunosuppression. The translation of immunomodulatory therapies has been hampered by the disease’s extreme heterogeneity. This review synthesizes
Yiting Xiao, Yiting Xiao, Yiting Xiao, Liyun Xu, Liyun Xu, Liyun Xu, Yuan Jiang, Yuan Jiang, Yuan Jiang, Qian Wang, Qian Wang, Qian Wang, Jie Deng, Jie Deng, Jie Deng, Zixiang Luo, Zixiang Luo, Zixiang Luo, Wenchao Xie, Wenchao Xie, Wenchao Xie, Caihong Ye, Caihong Ye, Caihong Ye, Zhangrui Zeng, Zhangrui Zeng, Zhangrui Zeng   +26 more
doaj   +1 more source