Results 21 to 30 of about 3,265,759 (283)
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
Frontiers in Chemistry, 2022 Targeting proteins’ enzymatic functions with small molecule inhibitors, as well as functions of receptor proteins with small-molecule agonists and antagonists, were the major forms of small-molecule drug development.
Liena Qin +4 more
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, 2023 What's Changed New Features Add a LinkSameWithUnits class that links respecting units by @astrofrog in https://github.com/glue-viz/glue/pull/2379 ### Bug Fixes Save legend state by @Carifio24 in https://github.com/glue-viz/glue/pull/2380 Fix bugs ...
Chris Beaumont +29 more
core +1 more source
, 2023 What's Changed New Features Relax longitude range in fullsphere projections by @Carifio24 in https://github.com/glue-viz/glue/pull/2348 ### Bug Fixes Update polar log transform test values to correct matplotlib 3.7 representation by @Carifio24 in https:/
Chris Beaumont +29 more
core +1 more source
, 2023 What's Changed New Features Add support for defining custom image stretches by @astrofrog in https://github.com/glue-viz/glue/pull/2423 ### Bug Fixes Set better starting xlim and ylim for custom viewers by @jfoster17 in https://github.com/glue-viz/glue ...
Chris Beaumont +25 more
core +1 more source
Chasing molecular glue degraders: screening approaches [PDF]
, 2022 Protein-protein interactions (PPIs) govern all biological processes. Some small molecules modulate PPIs through induced protein proximity. In particular, molecular glue degraders are monovalent compounds that orchestrate interactions between a target ...
Mayor-Ruiz, Cristina +3 more
core +1 more source
, 2023 <p><!-- Release notes generated using configuration in .github/release.yml at main --></p> <h2>What's Changed</h2> <h3>New Features</h3> <ul> <li>Support regions in image viewer by @jfoster17 in https:
Chris Beaumont +29 more
core +1 more source
Protein-Targeted Degradation Agents Based on Natural Products
Pharmaceuticals, 2022 Natural products are an important source of drug lead compounds, and natural products with significant biological activity are constantly being discovered and used in clinical practice.
Yan Li +4 more
doaj +1 more source
, 2023 <p><!-- Release notes generated using configuration in .github/release.yml at main --></p> <h2>What's Changed</h2> <h3>New Features</h3> <ul> <li>Customizable limits percentile and behavior on ...
Chris Beaumont +29 more
core +1 more source
, 2023 What's Changed Bug Fixes Add back parsing functions to qglue temporarily by @astrofrog in https://github.com/glue-viz/glue/pull/2435 Full Changelog: https://github.com/glue-viz/glue/compare/v1.13.0...v1.13.
Chris Beaumont +29 more
core +1 more source
SALL4: An Intriguing Therapeutic Target in Cancer Treatment
Cells, 2022 Spalt-Like Transcription Factor 4 (SALL4) is a critical factor for self-renewal ability and pluripotency of stem cells. On the other hand, various reports show tight relation of SALL4 to cancer occurrence and metastasis. SALL4 exerts its effects not only
Shiva Moein +3 more
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