Results 71 to 80 of about 12,554,924 (329)

Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data

open access: yesNucleic Acids Res., 2017
Model organism and human databases are rich with information about genetic and physical interactions. These data can be used to interpret and guide the analysis of results from new studies and develop new hypotheses.
Yanhui Hu   +7 more
semanticscholar   +1 more source

Unlabeled lysophosphatidic acid receptor binding in free solution as determined by a compensated interferometric reader

open access: yesJournal of Lipid Research, 2020
Native interactions between lysophospholipids (LPs) and their cognate LP receptors are difficult to measure because of lipophilicity and/or the adhesive properties of lipids, which contribute to high levels of nonspecific binding in cell membrane ...
Manisha Ray   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An automated method for finding molecular complexes in large protein interaction networks

open access: yesBMC Bioinformatics, 2003
BackgroundRecent advances in proteomics technologies such as two-hybrid, phage display and mass spectrometry have enabled us to create a detailed map of biomolecular interaction networks. Initial mapping efforts have already produced a wealth of data. As
Gary D. Bader, Christopher W. V. Hogue
semanticscholar   +1 more source

GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression

open access: yesFrontiers in Molecular Neuroscience, 2023
IntroductionGrowth-associated protein 43 (GAP-43) is known as a neuronal plasticity protein because it is widely expressed at high levels in neuronal growth cones during axonal regeneration.
Ye Ji Lee   +8 more
doaj   +1 more source

Dicistrovirus-Host Molecular Interactions

open access: yesCurrent Issues in Molecular Biology, 2019
Members of the family Dicistroviridae are small RNA viruses containing a monopartite positive-sense RNA genome. Dicistroviruses mainly infect arthropods, causing diseases that impact agriculture and the economy. In this chapter, we provide an overview of current and past research on dicistroviruses including the viral life cycle, viral translational ...
Warsaba, Reid   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Impact of nuclear vibrations on van der Waals and Casimir interactions at zero and finite temperature [PDF]

open access: yes, 2018
Van der Waals (vdW) and Casimir interactions depend crucially on material properties and geometry, especially at molecular scales, and temperature can produce noticeable relative shifts in interaction characteristics.
Hermann, Jan   +4 more
core   +2 more sources

Molecular interactions on microarrays

open access: yesNature Genetics, 1999
The structural features of nucleic acid probes tethered to a solid support and the molecular basis of their interaction with targets in solution have direct implication for the hybridization process. We discuss how arrays of oligonucleotides provide powerful tools to study the molecular basis of these interactions on a scale which is impossible using ...
Southern, E, Mir, K, Shchepinov, M
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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