Results 41 to 50 of about 4,145,178 (349)

Temperature perturbation model of the opto-galvanic effect in CO2-laser discharges [PDF]

, 1984
A detailed discharge model of the opto-galvanic effect in molecular laser gas mixtures is developed based on the temperature perturbation or discharge cooling mechanism of Smith and Brooks (1979).
A L S Smith, Ferguson A I, Goldsmith J E M, Meissner K W, Penning F M, S Moffatt, Shields H, Smith A L S, Smith A L S   +8 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Mechanism of Molecular Orientation by Single-cycle Pulses

, 2012
Significant molecular orientation can be achieved by time-symmetric single-cycle pulses of zero area, in the THz region. We show that in spite of the existence of a combined time-space symmetry operation, not only large peak instantaneous orientations ...
Bunker P. R., Juan Ortigoso, Moiseyev N.
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Hypoglycemic Effect of Pleurotus citrinopileatus and Hericium erinaceus Buccal Tablets on Diabetic Mice

Biology
Diabetes mellitus poses a global health challenge, necessitating natural adjuvants with minimal side effects. The aims of this study were to optimize the concentrations of chromium (Cr), zinc (Zn), and germanium (Ge) in the liquid fermentation media of ...
Zhongyi Yang, Kailu Zhang, Yan Liang, Kexin Shi, Jinqiang Ma, Juan Yu, Cunlong Lu, Aimin Liu, Xiancan Zhu   +8 more
doaj   +1 more source

Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates [PDF]

, 2018
Nitrogen-containing-bisphosphonates (N-BPs) are widely prescribed to treat osteoporosis and other bone-related diseases. Although previous studies established that N-BPs function by inhibiting the mevalonate pathway in osteoclasts, the mechanism by which
Abu-Remaileh, Monther, Horlbeck, Max A, O\u27Shea, Erin K, Park, Chong Yon, Peterson, Timothy R, Sabatini, David M, Surface, Lauren E, Weissman, Jonathan S, Wyant, Gregory A, Yu, Zhou   +9 more
core   +3 more sources

Mechanically interlocked molecular handcuffs

Chemical Science, 2022
Mechanically interlocked molecules that employ a handcuff component provide a pathway to highly unusual structures, a new nomenclature is proposed which helps to identify opportunities for employing this structural unit for new architectures.
Nicholas Pearce, Marysia Tarnowska, Nathan J. Andersen, Alexander Wahrhaftig-Lewis, Ben S. Pilgrim, Neil R. Champness   +5 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Genetic insights into therapeutic targets for aortic aneurysms: A Mendelian randomization study

EBioMedicine, 2022
Summary: Background: As aortic aneurysms (AAs) enlarge, they can become life-threatening if left undiagnosed or neglected. At present, there is a lack of radical treatments for preventing disease progression.
Yanghui Chen, Xin Xu, Linlin Wang, Ke Li, Yang Sun, Lei Xiao, Jiaqi Dai, Man Huang, Yan Wang, Dao Wen Wang   +9 more
doaj   +1 more source

New mechanism for non-trivial intra-molecular vibrational dynamics

, 2009
We investigate the time evolution process of one selected (initially prepared by optical pumping) vibrational molecular state, coupled to all other intra-molecular vibrational states of the same molecule, and also to its environment.
Benderskii, V. A., Kats, E. I.
core   +1 more source