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Mercury-induced toxicity: Mechanisms, molecular pathways, and gene regulation
Science of The Total EnvironmentMercury is a well-known neurotoxicant for humans and wildlife. The epidemic of mercury poisoning in Japan has clearly demonstrated that chronic exposure to methylmercury (MeHg) results in serious neurological damage to the cerebral and cerebellar cortex, leading to the dysfunction of the central nervous system (CNS), especially in infants exposed to ...
Bolun, Kang +3 more
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Molecular mechanisms of olfactory neuronal gene regulation.
Ciba Foundation symposium, 1994The mammalian olfactory system utilizes a biochemical cascade mediated by specialized proteins to detect odorants with high sensitivity and specificity. The recent identification of olfactory neuron-specific components for each step in the signalling cascade suggests that expression of these proteins is coordinately controlled by cis-acting regulatory ...
M M, Wang, R R, Reed
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Study of the molecular mechanisms in piRNA-mediated gene regulation
2023Από το CRISPR στους προκαρυώτες μέχρι και την παρεμβολή RNA (RNA interference, RNAi) στους ευκαρυώτες, μηχανισμοί που βασίζονται σε μικρά μόρια RNA, χρησιμοποιούνται εκτεταμένα για την άμυνα του ξενιστή ενάντια σε γονιδιωματικούς εισβολείς, όπως οι ιοί και τα μεταθετά στοιχεία (τρανσποζόνια). Τα τρανσποζόνια και οι ενδογενείς ρετροϊοί είναι αλληλουχίες
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Possible molecular-cellular mechanisms of the regulation of gene expression during learning
Neuroscience and Behavioral Physiology, 2000This study is an analysis of the regulatory mechanisms of plasticity. The first part provides a short review of the role of DNA-binding transcription factors in possible regulatory pathways and their activity in the mechanisms of plasticity. Our own data obtained in studies of the molecular mechanisms underlying the formation of conditioned defensive ...
L N, Grinkevich, G V, Vasil'ev
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Molecular mechanisms of gene regulation studied by site-directed spin labeling
Methods, 2003The technique of site-directed spin labeling using cysteine substitution mutagenesis followed by modification of the sulfhydryl group with a nitroxide reagent is emerging as a valuable alternative for the determination of protein folds and conformational changes in a variety of systems.
Heinz Jürgen, Steinhoff, Beatrix, Suess
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Molecular mechanism of rat NHE3 gene promoter regulation by sodium butyrate
American Journal of Physiology-Cell Physiology, 2007Sodium butyrate (NaB) stimulates sodium and water absorption by inducing colonic Na+/H+ exchange. NaB induces Na+/H+ exchanger (NHE)3 activity and protein and mRNA expression both in vivo and in vitro. Our previously published observations indicated that this induction is Ser/Thr kinase dependent and that NaB-responsive elements were localized within −
Pawel R, Kiela +6 more
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Molecular Mechanisms and Gene Regulation of Melanic Plumage Coloration in Birds
Russian Journal of Genetics, 2021Melanin-based plumage coloration in birds is determined by the ratio and distribution in the feathers of two types of melanin pigments, eumelanin and pheomelanin. The review focuses on different aspects of melanogenesis and transport and deposition of melanins, as well as on gene regulation of numerous processes associated with them. Modern concepts on
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Nuclear compartmentalization as a mechanism of quantitative control of gene expression
Nature reviews. Molecular cell biology, 2021Prashant Bhat, D. Honson, M. Guttman
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American Journal of Physiology - Gastrointestinal and Liver Physiology, 2001
S. Clarke
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S. Clarke
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Gene
Mycoplasma spp. are genome-reduced bacteria, many of which are pathogenic for humans and livestock. The mechanisms driving host colonization and pathogenicity for mycoplasmas remain only partially understood. These processes are influenced by both genomic factors, such as variations in gene content and organization, and regulatory mechanisms that ...
Jéssica Andrade Paes +1 more
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Mycoplasma spp. are genome-reduced bacteria, many of which are pathogenic for humans and livestock. The mechanisms driving host colonization and pathogenicity for mycoplasmas remain only partially understood. These processes are influenced by both genomic factors, such as variations in gene content and organization, and regulatory mechanisms that ...
Jéssica Andrade Paes +1 more
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