Results 141 to 150 of about 358,120 (301)
Sterically driven current reversal in a molecular motor model. [PDF]
Proc Natl Acad Sci U S A, 2023 Albaugh A, Gu G, Gingrich TR.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Translating the action of molecular motors to supramolecular polymers
Aggregate, 2022 Magda M. J. Dekker, Ghislaine Vantomme
doaj +1 more source
Excited-State Dynamics Simulations of a Light-Driven Molecular Motor in Solution. [PDF]
J Phys Chem A, 2023 Wen J, Mai S, González L.
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Examining mechanisms underlying the selective vulnerability of motor units in a mouse model of Spinal Muscular Atrophy [PDF]
, 2014 Spinal Muscular Atrophy (SMA) is a childhood form of motor neuron disease that causes a progressive paralysis that, in its most severe form, results in death before two years of age. There is currently no cure or treatment for SMA.
Thomson, Sophie Rose
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Synthetic molecular motor activates drug delivery from polymersomes. [PDF]
Proc Natl Acad Sci U S A, 2023 Guinart A +8 more
europepmc +1 more source
Photochemistry: Molecular motor speed limits
, 2012 To improve the efficiency of molecular motors, a better understanding of the dynamics of their functional motions is required. Now, ultrafast fluorescence spectroscopy has been used to monitor the excited-state evolution of a light-driven molecular ...
Miller, R.
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Defining Unidirectional Motions and Structural Reconfiguration in a Macrocyclic Molecular Motor. [PDF]
J Am Chem Soc, 2023 Regen-Pregizer BL, Dube H.
europepmc +1 more source