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Physics of Life Reviews, 2009
Most of the essential cellular processes such as polymerisation reactions, gene expression and regulation are governed by mechanical processes. Controlled mechanical investigations of these processes are therefore required in order to take our understanding of molecular biology to the next level. Single-molecule manipulation and force spectroscopy have
Jens, Michaelis +4 more
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Most of the essential cellular processes such as polymerisation reactions, gene expression and regulation are governed by mechanical processes. Controlled mechanical investigations of these processes are therefore required in order to take our understanding of molecular biology to the next level. Single-molecule manipulation and force spectroscopy have
Jens, Michaelis +4 more
openaire +2 more sources
Nature, 1994
What is the molecular basis of cell movement and changes in cell shape? The integration of three approaches is revealing how the molecular motors that drive these processes move and produce force.
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What is the molecular basis of cell movement and changes in cell shape? The integration of three approaches is revealing how the molecular motors that drive these processes move and produce force.
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Biological Physics 2000, 2001
The movements of cytoskeletal motors such as kinesin or myosin V cover many length and time scales. When such a motor is bound to a filament, the consumption of a single fuel molecule leads to a certain motor displacement or step which is of the order of several nanometers. The motor typically makes about a hundred such steps in its bound state and, in
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The movements of cytoskeletal motors such as kinesin or myosin V cover many length and time scales. When such a motor is bound to a filament, the consumption of a single fuel molecule leads to a certain motor displacement or step which is of the order of several nanometers. The motor typically makes about a hundred such steps in its bound state and, in
openaire +2 more sources
Molecular Motors: Cooperative Phenomena of Multiple Molecular Motors
2014Transport of various types of cargoes in cells is based on molecular motors moving along the cytoskeleton. Often, these motors work in teams rather than as isolated molecules. This chapter discusses analytical and computational approaches to study the cooperation of multiple molecular motors theoretically.
Klumpp, S. +3 more
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