Results 71 to 80 of about 35,392 (293)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Prolonged function and optimization of actomyosin motility for upscaled network-based biocomputation

open access: yesNew Journal of Physics, 2021
Significant advancements have been made towards exploitation of naturally available molecular motors and their associated cytoskeletal filaments in nanotechnological applications. For instance, myosin motors and actin filaments from muscle have been used
Aseem Salhotra   +9 more
doaj   +1 more source

Light-Driven Rotary Molecular Motors on Gold Nanoparticles

open access: yes, 2008
We report the synthesis of unidirectional light-driven rotary molecular motors based on chiral overcrowded alkenes and their immobilisation on the surface of gold nanoparticles through two anchors.
Brom, Coenraad R. van den,   +15 more
core   +1 more source

Molecular Motors in Aqueous Environment [PDF]

open access: yes, 2018
Molecular motors are Nature's solution for (supra)molecular transport and muscle functioning and are involved in most forms of directional motion at the cellular level.
Ben L. Feringa (1429174)   +10 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Development and optimization of an injectable in-situ gel system for sustained release of anti-tuberculosis drugs

open access: yesScientific Reports
Addressing the challenges of drug-resistant Mycobacterium tuberculosis requires regular drug intake and consistent therapeutic drug concentrations, for which in-situ gel systems offer a promising solution by enabling sustained drug release.
Pooraniammal Balu   +5 more
doaj   +1 more source

A Simple Experimental Model to Investigate Force Range for Membrane Nanotube Formation

open access: yesFrontiers in Materials, 2016
The presence of membrane tubules in living cells is essential to many biological processes. In cells, one mechanism to form nano-sized lipid tubules is via molecular motor induced bilayer extraction. In this paper, we describe a simple experimental model
Chai eLor   +4 more
doaj   +1 more source

The role of motor proteins in endosomal sorting [PDF]

open access: yes, 2011
Microtubule motor proteins play key roles in the spatial organization of intracellular organelles as well as the transfer of material between them.
Hunt, Sylvie   +3 more
core   +1 more source

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