Results 111 to 120 of about 342,935 (312)

Phylogenomics and barcoding of Panax: toward the identification of ginseng species

BMC Evolutionary Biology, 2018
Background The economic value of ginseng in the global medicinal plant trade is estimated to be in excess of US$2.1 billion. At the same time, the evolutionary placement of ginseng (Panax ginseng) and the complex evolutionary history of the genus is ...
V. Manzanilla, A. Kool, L. Nguyen Nhat, H. Nong Van, H. Le Thi Thu, H. J. de Boer   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The complete mitochondrial genome and phylogenetic analysis of Leptobotia bellacauda (Teleostei: Cypriniformes: Botiidae)

Mitochondrial DNA. Part B. Resources
The complete mitochondrial genome of Leptobotia bellacauda was sequenced and characterized for the first time. The mitogenome was a 16,591 bp circular molecule, including 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two ribosomal RNA ...
YiJun Li, Xiaoge Yang, Mengqi Liao, Zhihua Zhong, Yuxi Lian   +4 more
doaj   +1 more source

Biogeographic history of the endangered dwarf buffalo, subgenus Anoa (Bovidae: Bubalus quarlesi and Bubalus depressicornis): a perspective based on mitochondrial DNA phylogeny [PDF]

Evolutionary Systematics
The Anoa, including the Mountain Anoa (Bubalus quarlesi) and the Lowland Anoa (Bubalus depressicornis) according to current taxonomy, are endangered bovid species endemic to the tropical island of Sulawesi.
Dwi Sendi Priyono, Dedy Duryadi Solihin, Achmad Farajallah, Bambang Purwantara   +3 more
doaj   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Turkish Salix species: Molecular phylogeny and morphology

Forestist, 2020
Pelin Acar, Bircan Taşkıran, Funda Ö. Değirmenci, Zeki Kaya   +3 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Assessing Molecular Phylogenies [PDF]

Science, 1995
M. Nei, N. Takezaki, T. Sitnikova
openaire   +3 more sources