Results 51 to 60 of about 631,116 (314)

Nanotechnology and molecular cytogenetics: the future has not yet arrived [PDF]

, 2010
Quantum dots (QDs) are a novel class of inorganic fluorochromes composed of nanometer-scale crystals made of a semiconductor material. They are resistant to photo-bleaching, have narrow excitation and emission wavelengths that can be controlled by ...
Ioannou, Dimitris, Griffin, Darren K.
core   +1 more source

Multi-cohort analysis and experimental study on the function of squalene epoxidase as a ferroptosis inhibitor in HCC

BMC Cancer
Squalene epoxidase (SQLE) drives hepatocellular carcinoma (HCC) development via increased hepatic oxidative stress, a hallmark of ferroptosis. Although investigations have progressed, the precise link between SQLE and ferroptosis in HCC remains ...
Xun Yang, Yidi Wu, Qingxin Zhang, Yunfei Zhou, Shuyuan Chang, Chunhui Zhang, Dabin Liu   +6 more
doaj   +1 more source

Menin–MLL1 Interaction Small Molecule Inhibitors: A Potential Therapeutic Strategy for Leukemia and Cancers

Molecules, 2023
Encoded by the MEN1 gene, menin protein is a fusion protein that is essential for the oncogenic transformation of mixed-lineage leukemia (MLL) and leads to acute leukemia (AL). Therefore, accumulating evidence has demonstrated that inhibition of the high-
Qing Shi, Meiqi Xu, Zhijian Kang, Manjie Zhang, Yakun Luo   +4 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Comparison of quantitative real time PCR with Sequencing and ribosomal RNA-FISH for the identification of fungi in Formalin fixed, paraffin-embedded tissue specimens [PDF]

, 2011
Background: Identification of the causative agents of invasive fungal infections (IFI) is critical for guiding antifungal therapy. Cultures remain negative in a substantial number of IFI cases.
Rickerts Volker, Ko Daisy L, Fredricks, David N., Prasanna D Khot, David N Fredricks, David Myerson, Khot Prasanna D, Myerson David, Ko, Daisy L., Khot, Prasanna D., Myerson, David, Volker Rickerts, Lambrecht, Evelyn, Lambrecht Evelyn, Rickerts, Volker, Fredricks David N, Daisy L Ko, Evelyn Lambrecht   +17 more
core   +1 more source

Identification of sulfhydryl-containing proteins and further evaluation of the selenium-tagged redox homeostasis-regulating proteins

Redox Biology
Chemoproteomic profiling of sulfhydryl-containing proteins has consistently been an attractive research hotspot. However, there remains a dearth of probes that are specifically designed for sulfhydryl-containing proteins, possessing sufficient reactivity,
Zhongyao Jiang, Yue Tang, Jun Lu, Chang Xu, Yaxin Niu, Guanglu Zhang, Yanmei Yang, Xiufen Cheng, Lili Tong, Zhenzhen Chen, Bo Tang   +10 more
doaj   +1 more source

Probing Decoherence in Molecular 4f Qubits [PDF]

Chemical Science
We probe herein the fundamental factors that induce decoherence in ensembles of molecular magnetic materials.
Steen H. Hansen, Christian D. Buch, Jonatan B. Petersen, Michelle Rix, Marc Ubach Cervera, Asger Strandfelt, Richard E. P. Winpenny, Eric J. L. McInnes, Stergios Piligkos   +8 more
openaire   +4 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Inverse Mixed-Solvent Molecular Dynamics for Visualization of the Residue Interaction Profile of Molecular Probes

, 2022
To ensure efficiency in discovery and development, the application of computational technology is essential. Although virtual screening techniques are widely applied in the early stages of drug discovery research, the computational methods used in lead ...
Kudo, Genki, Yoshino, Ryunosuke, Keisuke Yanagisawa, Takatsugu Hirokawa, Yanagisawa, Keisuke, Hirokawa, Takatsugu, Ryunosuke Yoshino, Genki Kudo   +7 more
core   +1 more source

Fluorescent Imaging for Cysteine Detection In Vivo with High Selectivity

ChemistryOpen, 2019
As an essential amino acid, cysteine is involved in various biosynthetic and metabolic processes, such as protein synthesis, hormone synthesis, and redox homeostatic maintenance. Inordinate cysteine levels are often associated with serious diseases. Thus,
Zhuwen Duan, Youming Zhu, Yuyun Yang, Zixu He, Prof. Ju Liu, Prof. Ping Li, Dr. Hui Wang, Prof. Bo Tang   +7 more
doaj   +1 more source