Results 41 to 50 of about 1,377,862 (341)

A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era. Selecting cases, matching clinical benefit. A position paper from the Italian Group of Haematopathology (G.I.E.) [PDF]

open access: yes, 2019
An accurate diagnosis of clinically distinct subgroups of aggressive mature B cell lymphomas is crucial for the choice of proper treatment. Presently, precise recognition of these disorders relies on the combination of morphological, immunophenotypical ...
Agostinelli, C.   +17 more
core   +2 more sources

Synthesis of Chiral Helic[1]triptycene[3]arenes and Their Enantioselective Recognition towards Chiral Guests Containing Aminoindan Groups

open access: yesMolecules, 2021
Starting from the enantiopure precursors, a pair of chiral macrocyclic arenes named helic[1]triptycene[3]arenes were conveniently synthesized. The circular dichroism (CD) spectra of the enantiomeric macrocyclic arenes exhibited mirror images, and the X ...
Jing Li, Ying Han, Chuan-Feng Chen
doaj   +1 more source

Molecular Recognition in a Thermoplastic Elastomer

open access: yesJournal of the American Chemical Society, 2005
Selective incorporation of bisurea guests in thermoplastic elastomers with poly(tetrahydrofuran) soft blocks and bisurea containing hard blocks is observed when the distances between the urea groups of host and guest match. The incorporation leads to significant modulation of mechanical properties.
Koevoets, R.A.   +5 more
openaire   +6 more sources

Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle [PDF]

open access: yes, 2014
Inflammation is the ultimate response to the constant challenges of the immune system by microbes, irritants or injury. The inflammatory cascade initiates with the recognition of microorganism-derived pathogen associated molecular patterns (PAMPs) and ...
Abe   +100 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Molecular Recognition [PDF]

open access: yesChemPhysChem, 2021
Tiddo Jonathan Mooibroek   +2 more
openaire   +4 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1. [PDF]

open access: yes, 2018
Polybromo-1 (PBRM1) is an important tumor suppressor in kidney cancer. It contains six tandem bromodomains (BDs), which are specialized structures that recognize acetyl-lysine residues.
Alicea-Velázquez, Nilda L.   +10 more
core   +2 more sources

Peptide Linker Affecting the Activity Retention Rate of VHH in Immunosorbents

open access: yesBiomolecules, 2020
VHH-based immunosorbents are an emerging and promising tool for the removal of toxic substances from plasma. However, the small size of VHHs is a double-edged sword, bringing both benefits and drawbacks to the immunosorbent.
Da Li   +5 more
doaj   +1 more source

Decoration of Fe3+ on carboxyl microporous organic network to fabricate magnetic porous carbon for efficient adsorption and removal of cationic dyes

open access: yesChemical Engineering Journal Advances, 2021
Fabrication of novel magnetic porous materials for efficient magnetic adsorption and removal of environmental contaminants still remains great important and interesting in environmental science.
Xin-Qiao He   +4 more
doaj   +1 more source

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