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BioTechniquesAs the volume of sequence data from variable pathogens increases, means of analyzing, annotating and extracting specific taxa for study becomes more difficult. To meet these challenges for datasets with hundreds to thousands of taxa, 'Phylobook' was developed.
Jeffrey C. Furlong +4 more
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, 2020 The uncovering and description of Earth’s biodiversity constitute an ongoing and incomplete chapter of the scientific endeavour. Fortunately, biodiversity studies have been greatly benefiting from molecular tools, such as DNA (meta)barcoding, which provide efficient identification tools for biomonitoring and conservation programmes.
João T. Fontes
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A Step-by-Step Computational Protocol for Functional Annotation and Structural Modelling of Insect Chemosensory Proteins [PDF]
Bio-ProtocolInsects rely on chemosensory proteins, including gustatory receptors, to detect chemical cues that regulate feeding, mating, and oviposition behaviours.
Rajeswari Kalepu +4 more
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A Factor Graph Approach to Automated GO Annotation [PDF]
, 2016 As volume of genomic data grows, computational methods become essential for providing a first glimpse onto gene annotations. Automated Gene Ontology (GO) annotation methods based on hierarchical ensemble classification techniques are particularly ...
Elizabeth Tapia +4 more
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ChanFAD: A Functional Annotation Database for Ion Channels
Frontiers in Bioinformatics, 2022 Ion channels are integral membrane protein complexes critical for regulation of membrane potential, cell volume, and other signaling events. As complex molecular assemblies with many interacting partners, ion channels have multiple structural and ...
Elizabeth V. Castro +21 more
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Recent advancements in critical care: Part I
Indian Journal of Anaesthesia, 2023 Medical colleges are now developing or refurbishing their anaesthesia intensive care units. In most teaching colleges, the residency post includes working in the critical care unit (CCU).
Palepu B Gopal +5 more
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Embeddings from deep learning transfer GO annotations beyond homology
Scientific Reports, 2021 Knowing protein function is crucial to advance molecular and medical biology, yet experimental function annotations through the Gene Ontology (GO) exist for fewer than 0.5% of all known proteins.
Maria Littmann +4 more
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AnsNGS: An Annotation System to Sequence Variations of Next Generation Sequencing Data for Disease-Related Phenotypes [PDF]
Healthcare Informatics Research, 2013 ObjectivesNext-generation sequencing (NGS) data in the identification of disease-causing genes provides a promising opportunity in the diagnosis of disease.
Young-Ji Na, Yonglae Cho, Ju Han Kim
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MoBiDiC Prioritization Algorithm, a Free, Accessible, and Efficient Pipeline for Single-Nucleotide Variant Annotation and Prioritization for Next-Generation Sequencing Routine Molecular Diagnosis [PDF]
The Journal of Molecular Diagnostics, 2018 Interpretation of next-generation sequencing constitutes the main limitation of molecular diagnostics. In diagnosing myopathies and muscular dystrophies, another issue is efficiency in predicting the pathogenicity of variants identified in large genes, especially TTN; current in silico prediction tools show limitations in predicting and ranking the ...
Kevin Yauy +13 more
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Mitochondrial DNA. Part B. Resources, 2021 Ankistrodesmus falcatus strain UCP001 is a native oleaginous microalgae isolated from the Peruvian Amazon basin. In this study we sequenced, de novo assembled, and functionally annotated the complete mitochondrial genome of the native oleaginous ...
Marianela Cobos +11 more
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