Results 21 to 30 of about 254,467 (221)

3D profile-based approach to proteome-wide discovery of novel human chemokines. [PDF]

PLoS ONE, 2012
Chemokines are small secreted proteins with important roles in immune responses. They consist of a conserved three-dimensional (3D) structure, so-called IL8-like chemokine fold, which is supported by disulfide bridges characteristic of this protein ...
Aurelie Tomczak, Jana Sontheimer, David Drechsel, Rainer Hausdorf, Marc Gentzel, Andrej Shevchenko, Stefanie Eichler, Karim Fahmy, Frank Buchholz, M Teresa Pisabarro   +9 more
doaj   +1 more source

Non‐homology‐based prediction of gene functions in maize (Zea mays ssp. mays)

The Plant Genome, 2020
Advances in genome sequencing and annotation have eased the difficulty of identifying new gene sequences. Predicting the functions of these newly identified genes remains challenging.
Xiuru Dai, Zheng Xu, Zhikai Liang, Xiaoyu Tu, Silin Zhong, James C. Schnable, Pinghua Li   +6 more
doaj   +1 more source

Functional genome Annotation in Bacterial infections: A Review [PDF]

Al Ameen Journal of Medical Sciences, 2021
Functional annotation provides the information of gene about its biological identity and various types of molecular function and biological role like sub-cellular location and its expression.
Sharique Ahmad, Shivani Singh, Shriya Arora, Saurabh Srivastava   +3 more
doaj  

PROMPT: a protein mapping and comparison tool

BMC Bioinformatics, 2006
Background Comparison of large protein datasets has become a standard task in bioinformatics. Typically researchers wish to know whether one group of proteins is significantly enriched in certain annotation attributes or sequence properties compared to ...
Frishman Dmitrij, Schmidt Thorsten
doaj   +1 more source

Phylobook: a tool for display, clade annotation and extraction of sequences from molecular phylogenies

BioTechniques
As the volume of sequence data from variable pathogens increases, means of analyzing, annotating and extracting specific taxa for study becomes more difficult. To meet these challenges for datasets with hundreds to thousands of taxa, 'Phylobook' was developed.
Jeffrey C Furlong, Peter D Darley, Wenjie Deng, James I Mullins, Roger E Bumgarner   +4 more
openaire   +3 more sources

Short k-mer abundance profiles yield robust machine learning features and accurate classifiers for RNA viruses

PLoS ONE, 2020
High-throughput sequencing technologies have greatly enabled the study of genomics, transcriptomics and metagenomics. Automated annotation and classification of the vast amounts of generated sequence data has become paramount for facilitating biological ...
Md. Nafis Ul Alam, Umar Faruq Chowdhury, Ruslan Kalendar   +2 more
doaj   +2 more sources

Development of a panel of unigene-derived polymorphic EST–SSR markers in lentil using public database information

Crop Journal, 2016
Lentil (Lens culinaris Medik.), a diploid (2n = 14) with a genome size greater than 4000 Mbp, is an important cool season food legume grown worldwide. The availability of genomic resources is limited in this crop species.
Debjyoti Sen Gupta, Peng Cheng, Gaurav Sablok, Dil Thavarajah, Pushparajah Thavarajah, Clarice J. Coyne, Shiv Kumar, Michael Baum, Rebecca J. McGee   +8 more
doaj   +1 more source

Genomic Fishing and Data Processing for Molecular Evolution Research

Methods and Protocols, 2022
Molecular evolution analyses, such as detection of adaptive/purifying selection or ancestral protein reconstruction, typically require three inputs for a target gene (or gene family) in a particular group of organisms: sequence alignment, model of ...
Héctor Lorente-Martínez, Ainhoa Agorreta, Diego San Mauro   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Sequencing and characterizing the genome of Estrella lausannensis as an undergraduate project: training students and biological insights

Frontiers in Microbiology, 2015
With the widespread availability of high-throughput sequencing technologies, sequencing projects have become pervasive in the molecular life sciences.
Claire eBertelli, Claire eBertelli, Sébastien eAeby, Bérénice eChassot, James eClulow, Olivier eHilfiker, Samuel eRappo, Sébastien eRitzmann, Paolo eSchumacher, Céline eTerrettaz, Paola eBenaglio, Laurent eFalquet, Laurent eFalquet, Laurent eFarinelli, Walid eGharib, Walid eGharib, Alexander eGoesmann, Keith eHarshman, Burkhard eLinke, Ryo eMiyazaki, Carlo eRivolta, Marc eRobinson-Rechavi, Marc eRobinson-Rechavi, Jan Roelof eVan Der Meer, Gilbert eGreub   +24 more
doaj   +1 more source