Results 41 to 50 of about 5,099,016 (263)

Short k-mer abundance profiles yield robust machine learning features and accurate classifiers for RNA viruses

PLoS ONE, 2020
High-throughput sequencing technologies have greatly enabled the study of genomics, transcriptomics and metagenomics. Automated annotation and classification of the vast amounts of generated sequence data has become paramount for facilitating biological ...
Md. Nafis Ul Alam, Umar Faruq Chowdhury, Ruslan Kalendar   +2 more
doaj   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Development of a panel of unigene-derived polymorphic EST–SSR markers in lentil using public database information

Crop Journal, 2016
Lentil (Lens culinaris Medik.), a diploid (2n = 14) with a genome size greater than 4000 Mbp, is an important cool season food legume grown worldwide. The availability of genomic resources is limited in this crop species.
Debjyoti Sen Gupta, Peng Cheng, Gaurav Sablok, Dil Thavarajah, Pushparajah Thavarajah, Clarice J. Coyne, Shiv Kumar, Michael Baum, Rebecca J. McGee   +8 more
doaj   +1 more source

Genomic Fishing and Data Processing for Molecular Evolution Research

Methods and Protocols, 2022
Molecular evolution analyses, such as detection of adaptive/purifying selection or ancestral protein reconstruction, typically require three inputs for a target gene (or gene family) in a particular group of organisms: sequence alignment, model of ...
Héctor Lorente-Martínez, Ainhoa Agorreta, Diego San Mauro   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Human protein function prediction: application of machine learning for integration of heterogeneous data sources [PDF]

, 2010
Experimental characterisation of protein cellular function can be prohibitively expensive and take years to complete. To address this problem, this thesis focuses on the development of computational approaches to predict function from sequence.
Lobley, A.E.
core  

The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts [PDF]

, 2007
Here we report the new features and improvements in our latest release of the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/), a comprehensive annotation resource for human genes and transcripts.
Murakami, Katsuhiko, Shionyu, Masafumi, Nagata, Naoki, Tanaka, S., Kuryshev, Vladimir, Eveno, E., Mukai, Yuri, Imbeaud, S., Makalowski, W., Zhang, Q., Sakai, Katsunaga, Thomas, Michaeｌ A., Imanishi, T., Lee, Kyung-Bum, Tanaka, Masayuki, Thomas, M.A., Barrero, Roberto, Osanger, A., Tanaka, Susumu, Lenhard, B., Shiba, Rie, Sugano, S., Sakate, Ryuichi, Nakai, K., Wilming, L., Jia, Libin, Kawamura, Toshiyuki, Nishikawa, T., Thierry-Mieg, J., Kawahara, Yoshihiro, Harada, E., Kimura, K., Suzuki, Yutaka, Tanaka, Nobuhiko, Yasuda, T., Kawamura, T., Sanbonmatsu, Ryoko, Barrero, R.A., Yamaguchi, Kaori, Hide, Winston, Auffray, C., Horton, Paul, Niimura, Y., Shimoyama, Mary, Thomas, Michael, Tonellato, Peter, Hilton, P.B., Kikuno, Reiko, Kanno, Masako, Sugawara, Hideaki, Isogai, T., Sakai, Hiroaki, Whitfield, Eleanor, Nishikata, K., Matsuya, Aki, Halligan, B., Ohtsubo, Masafumi, Shiba, R., Fukuchi, S., Lee, K-B, Takabayashi, K., Sakate, R., Nurimoto, S., Kaneko, Yayoi, Nagasaki, H., Hayashizaki, Yoshihide, Lin, Yi-Chueh, Bellgard, M., Minoshima, Shinsei, Motono, C., Amid, Clara, Schupp, Ingo, Osato, N., Wagner, L., Isogai, Takao, Ohyanagi, H., Yura, Kei, Akiyama, Y., Jia, Ji, Yamaguchi, K., O’Donovan, C., Endo, T., O'Donovan, C., Matsuya, Akihiro, Yamamoto, N., Jin, L., Hirakawa, M., Chun, Hong-Woo, Makino, Takashi, Thierry-Mieg, D., Jia, L., Tada, Masahito, Twigger, Simon, Jin, Ji, Zhang, Qinghua, Nurimoto, Shin, Tamura, T., Bonaldo, M.D.F., Todokoro, Fusano, Nozaki, A., Ohara, Osamu, De Souza, Sandro J., Hayakawa, Yosuke, Nagata, N., Koyanagi, K.O., Gojobori, T., Kim, N-S, Yamasaki, Chisato, Shimoyama, M., Makalowska, I., Yoo, H-S, Lancet, D., Imbeaud, Sandrine, Takeda, Jun, Sanbonmatsu, R., Nakai, Kenta, Debily, Anne, Yura, K., Shionyu, M., Todokoro, F., Ikeo, K., Osanger, Andreas, Hanaoka, Hideki, Tanino, Motohiko, Eveno, Eric, Estreicher, Anne, Nozaki, Asami, Sugano, Sumio, O'Donovan, Claire, De Souza, S.J., Bonaldo, Maria de Fatima, Kikuno, R., Murakami, K., Mukai, Y., Lancet, Doron, Hayakawa, Y., Lin, Y., Ogura Noda, Akiko, Hashizume, A., Kim, Nam-Soon, Takeda, J., Thierry-Mieg, Jean, Koyanagi, Kanako O., Mashima, J., Hilton, Phillip, Nakao, M., Saitou, N., Ohtsubo, M., Niimura, Yoshihito, Takahashi, Aiko, Nishikawa, K., Suzuki, Yoshiyuki, Habara, Takuya, Kikugawa, S., Han, Michael, Kuryshev, V., Tamura, Takuro, Shimada, M., Ohyanagi, Hajime, Tanino, M., Tateno, Y., Yamaguchi-Kabata, Y., Sato, Y., Suzuki, Mami, Ikeo, Kazuho, Chiusano, Maria Luisa, Lenhard, Boris, Go, Mitiko, Taniya, Takayuki, Itoh, Takeshi, Takahashi, A., Hinz, Ursula, Kikugawa, Shingo, Hide, Hideaki, Tanaka, M., Matsuya, A., Amid, C., Hirakawa, Mika, Debily, M.A., Akiyama, Yutaka, Suzuki, Y., Hishiki, T., Nomura, N., Koyanagi, Kanako, Fujii, Y., Hinz, U., Sugawara, H., Saitou, Naruya, Zhang, J., Chakraborty, R., Debily, Marie Anne, Wagner, Lukas, Noda, Aki, Sakai, H., Schupp, I., Nishikata, Ken, Hanaoka, H., Miyazaki, S., Kaneko, Y., Kim, S., Habara, T., Tanaka, N., Hishiki, Teruyoshi, Minoshima, S., Satake, Ryuichi, Nakai, Ken, Lin, Y-C, Bellgard, Matthew, Yoo, H., Suwa, M., Nishikawa, Tetsuo, Chun, H., Nagasaki, H, Okido, T., Wiemann, S., Kawahara, Y., Hayashizaki, Y., Barrero, Roberto A., Nishikata, Kensaku, Miyazaki, Satoru, Soares, Marcelo Bento, Han, M., Chen, Z., Kikugawa, Shin, Whitfield, E., Debily, M., Hide, W., Takabayashi, Kazuhiko, Fukuchi, Satoshi, Motono, Chie, Yoo, Hyang-Sook, Tada, M., Fujii, Yasuyuki, Nomura, Nobuo, Estreicher, A., Auffray, Charles, Gough, Craig, Tonellato, P., Wilming, Laurens, Mashima, Jun, Wiemann, Stefan, Ohara, O., Graudens, E., Hanada, Kousuke, Hashizume, Aki, Go, M., Zhang, Ji, Gough, C., Noda, A.O., Yasuda, Tomohiro, Chen, Zhu, Graudens, Esther, Nakao, Mitsuteru, Imanishi, Tadashi, Harada, Erimi, Kimura, Kouichi, Suwa, Makiko, Nagasaki, Hideki, Hilton, Philip B., Yamaguchi-Kabata, Yumi, Chiusano, M.L., Kulikova, T., Yamamoto, Naoyuki, Chakraborty, Ranajit, Saichi, Naomi, Kim, Sangsoo, Kulikova, Tamara, Makalowska, Izabela, Thierry-Mieg, Danielle, Suzuki, M., Taniya, T., Sakai, K., Okido, Toshihisa, Halligan, Brian, Chun, H-W, Twigger, S., De Souza, Sandro, Takeda, Jun-ichi, Yamasaki, C., Makino, T., Tiffin, Nicola, Nishikawa, Ken, Gojobori, Takashi, Kanno, M., Shimada, Makoto, Makalowski, Wojciech, Horton, P., Hanada, K., Tiffin, N., Osato, Naoki, Sato, Yoshiharu, Tateno, Yoshio, Saichi, N., Takeda, J-I, Jin, Lihua, Endo, Toshinori, Bonaldo, M., Soares, M.B., Itoh, T., Lee, K., Kim, N., K Murakami, T Imanishi, T Gojobori, Hyang Sook Yoo, Nam-Soon Kim, Y Sato, E Harada, J Takeda, Y Fujii, S Kim, C Yamasaki   +311 more
core   +1 more source

Sequencing and characterizing the genome of Estrella lausannensis as an undergraduate project: training students and biological insights

Frontiers in Microbiology, 2015
With the widespread availability of high-throughput sequencing technologies, sequencing projects have become pervasive in the molecular life sciences.
Claire eBertelli, Claire eBertelli, Sébastien eAeby, Bérénice eChassot, James eClulow, Olivier eHilfiker, Samuel eRappo, Sébastien eRitzmann, Paolo eSchumacher, Céline eTerrettaz, Paola eBenaglio, Laurent eFalquet, Laurent eFalquet, Laurent eFarinelli, Walid eGharib, Walid eGharib, Alexander eGoesmann, Keith eHarshman, Burkhard eLinke, Ryo eMiyazaki, Carlo eRivolta, Marc eRobinson-Rechavi, Marc eRobinson-Rechavi, Jan Roelof eVan Der Meer, Gilbert eGreub   +24 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evolutionary Genomics of Staphylococcus aureus Reveals Insights into the Origin and Molecular Basis of Ruminant Host Adaptation [PDF]

, 2010
Phenotypic biotyping has traditionally been used to differentiate bacteria occupying distinct ecological niches such as host species. For example, the capacity of Staphylococcus aureus from sheep to coagulate ruminant plasma, reported over 60 years ago ...
Fitzgerald J.R., Smyth, D.S., Jodi A. Lindsay, Lindsay, J.A., Hinds, Jason, Davida S. Smyth, Tormo-Mas, Maria A, Gould, Katherine A, Jonathan P. Bollback, Rambaut, A, Ben Zakour, N.L., Cyril J Smyth, Fitzgerald, Ross; id_orcid, Lowder, Bethan V., Hinds J., Penades, Jose R, J Ross Fitzgerald, Witney, A., Rambaut A., Katherine A. Gould, Hinds, J, Bollback, J.P., Jason Hinds, J. Ross Fitzgerald, Tormo-Mas, María A., Smyth D.S., Nouri L Ben Zakour, Penades J.R., Jonathan P Bollback, Weinert, Lucy A, Caitriona M. Guinane, Nouri L. Ben Zakour, Bethan V Lowder, Smyth, Davida S, Davida S Smyth, Gould, KA, Guinane, C.M., Rambaut, A., Lowder B.V., Lowder, BV, Cartwright, R.A., Fitzgerald, J. Ross, Lindsay, Jodi A, Cyril J. Smyth, Cartwright R.A., Tormo-Mas, MA, Ben Zakour, Nouri L., Weinert, LA, Tormo-Mas, M.A., Gould, Katherine A., Maria A. Tormo-Mas, Caitriona M Guinane, Penades, JR, Smyth, Cyril J., Gould, K.A., Smyth, C.J., Smyth, Cyril J, Cartwright, RA, Lucy A. Weinert, Fitzgerald, JR, Penades, J.R., Cartwright, Robyn, Bethan V. Lowder, Ben Zakour, NL, Lindsay, JA, Smyth C.J., Andrew Rambaut, Gould K.A., Jodi A Lindsay, Weinert, Lucy A., Guinane, Caitriona M., Witney, Adam, Bollback J.P., Hinds, J., Bollback, Jonathan P., Lowder, Bethan V, Guinane, CM, Katherine A Gould, Witney, A, Guinane C.M., Lowder, B.V., Weinert L.A., Lindsay J.A., Robyn A. Cartwright, Tormo-Mas M.A., Maria A Tormo-Mas, Lindsay, Jodi A., Smyth, DS, Weinert, L.A., Bollback, Jonathan P, Lucy A Weinert, Ben Zakour, Nouri L, Bollback, JP, Witney A., Rambaut, Andrew, Penadés, José R., Smyth, CJ, Zakour N.L.B., José R Penadé S, Guinane, Caitriona M, Fitzgerald, J.R., Cartwright, Robyn A, Fitzgerald, J Ross, Adam Witney, Cartwright, Robyn A., Robyn A Cartwright, José R. Penadés   +106 more
core   +2 more sources