Results 31 to 40 of about 261,045 (224)

Sequencing and characterizing the genome of Estrella lausannensis as an undergraduate project: training students and biological insights

Frontiers in Microbiology, 2015
With the widespread availability of high-throughput sequencing technologies, sequencing projects have become pervasive in the molecular life sciences.
Claire eBertelli, Claire eBertelli, Sébastien eAeby, Bérénice eChassot, James eClulow, Olivier eHilfiker, Samuel eRappo, Sébastien eRitzmann, Paolo eSchumacher, Céline eTerrettaz, Paola eBenaglio, Laurent eFalquet, Laurent eFalquet, Laurent eFarinelli, Walid eGharib, Walid eGharib, Alexander eGoesmann, Keith eHarshman, Burkhard eLinke, Ryo eMiyazaki, Carlo eRivolta, Marc eRobinson-Rechavi, Marc eRobinson-Rechavi, Jan Roelof eVan Der Meer, Gilbert eGreub   +24 more
doaj   +1 more source

Whole genome sequence and annotation dataset of rare actinobacteria, Barrientosiimonas humi gen. nov., sp. nov. 39T from Antarctica

Data in Brief, 2023
Barrientosiimonas humi gen. nov., sp. nov. 39T is a rare actinobacteria strain isolated from the less explored extreme environment of the Antarctic soil.
Sin Yee Chong, Aida Azrina Azmi, Yoke Kqueen Cheah   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Comparative analysis of grapevine whole-genome gene predictions, functional annotation, categorization and integration of the predicted gene sequences

BMC Research Notes, 2012
Background The first draft assembly and gene prediction of the grapevine genome (8X base coverage) was made available to the scientific community in 2007, and functional annotation was developed on this gene prediction.
Grimplet Jérôme, Van Hemert John, Carbonell-Bejerano Pablo, Díaz-Riquelme José, Dickerson Julie, Fennell Anne, Pezzotti Mario, Martínez-Zapater José M   +7 more
doaj   +1 more source

Annotation of yellow genes in Diaphorina citri, the vector for Huanglongbing disease

GigaByte, 2021
Huanglongbing (HLB), also known as citrus greening disease, is caused by the bacterium Candidatus Liberibacter asiaticus (CLas). It is a serious threat to global citrus production.
Crissy Massimino, Chad Vosburg, Teresa Shippy, Prashant S. Hosmani, Mirella Flores-Gonzalez, Lukas A. Mueller, Wayne B. Hunter, Joshua B. Benoit, Susan J. Brown, Tom D’Elia, Surya Saha   +10 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Novel tools for conservation genomics: comparing two high-throughput approaches for SNP discovery in the transcriptome of the European hake. [PDF]

PLoS ONE, 2011
The growing accessibility to genomic resources using next-generation sequencing (NGS) technologies has revolutionized the application of molecular genetic tools to ecology and evolutionary studies in non-model organisms. Here we present the case study of
Ilaria Milano, Massimiliano Babbucci, Frank Panitz, Rob Ogden, Rasmus O Nielsen, Martin I Taylor, Sarah J Helyar, Gary R Carvalho, Montserrat Espiñeira, Miroslava Atanassova, Fausto Tinti, Gregory E Maes, Tomaso Patarnello, FishPopTrace Consortium, Luca Bargelloni   +14 more
doaj   +1 more source

Fully automated annotation of mitochondrial genomes using a cluster-based approach with de Bruijn graphs

Frontiers in Genetics, 2023
A wide range of scientific fields, such as forensics, anthropology, medicine, and molecular evolution, benefits from the analysis of mitogenomic data. With the development of new sequencing technologies, the amount of mitochondrial sequence data to be ...
Lisa Fiedler, Martin Middendorf, Matthias Bernt   +2 more
doaj   +1 more source