The Plant Genome, 2020 Most of the bioinformatics tools for enzyme annotation focus on enzymatic function assignments. Sequence similarity to well‐characterized enzymes is often used for functional annotation and to assign metabolic pathways.
Rodrigo de Oliveira Almeida +1 more
doaj +1 more source
Characterization of the transcriptome and EST-SSR development in Boea clarkeana, a desiccation-tolerant plant endemic to China [PDF]
PeerJ, 2017 Background Desiccation-tolerant (DT) plants can recover full metabolic competence upon rehydration after losing most of their cellular water (>95%) for extended periods of time.
Ying Wang +4 more
doaj +2 more sources
Polymorphism identification and improved genome annotation of Brassica rapa through Deep RNA sequencing. [PDF]
, 2014 The mapping and functional analysis of quantitative traits in Brassica rapa can be greatly improved with the availability of physically positioned, gene-based genetic markers and accurate genome annotation.
Covington, Michael F +4 more
core +1 more source
TriAnnot: a versatile and high performance pipeline for the automated annotation of plant genomes
Frontiers in Plant Science, 2012 In support of the international effort to obtain a reference sequence of the bread wheat genome and to provide plant communities dealing with large and complex genomes with a versatile, easy-to-use online automated tool for annotation, we have developed ...
Philippe eLeroy +23 more
doaj +1 more source
The development of non-coding RNA ontology [PDF]
, 2016 Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data ...
Blake, Judith +15 more
core +1 more source
Missense-depleted regions in population exomes implicate ras superfamily nucleotide-binding protein alteration in patients with brain malformation. [PDF]
, 2016 Genomic sequence interpretation can miss clinically relevant missense variants for several reasons. Rare missense variants are numerous in the exome and difficult to prioritise. Affected genes may also not have existing disease association.
Dumas, Kevin +13 more
core +7 more sources
The Genome and Methylome of a Subsocial Small Carpenter Bee, Ceratina calcarata [PDF]
, 2016 Understanding the evolution of animal societies, considered to be a major transition in evolution, is a key topic in evolutionary biology. Recently, new gateways for understanding social evolution have opened up due to advances in genomics, allowing for ...
Glastad, Karl M. +3 more
core +2 more sources
Cross-phyla protein annotation by structural prediction and alignment
Genome Biology, 2023 Background Protein annotation is a major goal in molecular biology, yet experimentally determined knowledge is typically limited to a few model organisms.
Fabian Ruperti +5 more
doaj +1 more source
A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]
, 2019 Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn +11 more
core +2 more sources
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
BMC Bioinformatics, 2010 Background One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of the selective advantage, and thus a functional annotation, of (co-)mutations ...
Hamacher Kay +2 more
doaj +1 more source