Results 91 to 100 of about 2,703,182 (313)

Phase transition in the sample complexity of likelihood-based phylogeny inference

open access: yes, 2017
Reconstructing evolutionary trees from molecular sequence data is a fundamental problem in computational biology. Stochastic models of sequence evolution are closely related to spin systems that have been extensively studied in statistical physics and ...
Roch, Sebastien, Sly, Allan
core   +1 more source

The EM Algorithm and the Rise of Computational Biology [PDF]

open access: yes, 2010
In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link   +3 more
core   +3 more sources

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

Pandemic Strain of Foot-and-Mouth Disease Virus Serotype O

open access: yesEmerging Infectious Diseases, 2005
A particular genetic lineage of foot-and-mouth disease virus (FMDV) serotype O, which we have named the PanAsia strain, was responsible for an explosive pandemic in Asia and extended to parts of Africa and Europe from 1998 to 2001. In 2000 and 2001, this
Nick J. Knowles   +4 more
doaj   +1 more source

Re-collection of Dermea prunus in China, with a description of D. chinensis sp. nov. [PDF]

open access: yesMycoKeys, 2019
Dermea was protected against its synonym, Foveostroma, due to its well-circumscribed generic concept and more frequent use. We describe and illustrate Dermea chinensis sp. nov.
Ning Jiang, Cheng-Ming Tian
doaj   +3 more sources

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

open access: yesFEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka   +6 more
wiley   +1 more source

Resurrection of the genus Staphisagria J. Hill, sister to all the other Delphinieae (Ranunculaceae) [PDF]

open access: yes, 2011
Molecular sequence data show that the three species of Delphinium subg. Staphisagria (J. Hill) Peterm. form the sister clade to Aconitum L., Aconitella Spach, Consolida (DC.) S.F. Gray, and all remaining species of Delphinium L.
Jabbour, Florian, Renner, Susanne S.
core   +3 more sources

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

On the progenitor of V838 Monocerotis

open access: yes, 2005
We summarize and analyze the available observational data on the progenitor and the enviroment of V838 Mon. From the available photometric data for the progenitor of V838 Mon we exclude the possibility that the object before eruption was an evolved red ...
Abell   +40 more
core   +1 more source

Exploring the temporal structure of heterochronous sequences using TempEst (formerly Path-O-Gen) [PDF]

open access: yes, 2016
Gene sequences sampled at different points in time can be used to infer molecular phylogenies on a natural timescale of months or years, provided that the sequences in question undergo measurable amounts of evolutionary change between sampling times ...
Lam, Tommy T.   +3 more
core   +1 more source

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