Results 91 to 100 of about 2,823,273 (337)
Methods in Ecology and EvolutionArchival DNA samples collected and analysed for a range of research and applied questions have accumulated in the laboratories of universities, government agencies and commercial service providers for decades. These DNA archives represent a valuable, yet
K. M. Sumby +4 more
doaj +1 more source
GenFlow: generic flow for integration, management and analysis of molecular biology data
Genetics and Molecular Biology, 2004 A large number of DNA sequencing projects all over the world have yielded a fantastic amount of data, whose analysis is, currently, a big challenge for computational biology.
Marcio Katsumi Oikawa +4 more
doaj +1 more source
BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]
, 2009 A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ari, Eszter +4 more
core +1 more source
Experimental & Applied Acarology, 1992 DNA sequence data were used to examine phylogenetic relationships between six species of economically important Tetranychidae mites: Eotetranychus carpini (Oudemans), E. pruni (Reck), Tetranychus pacificus McGregor, T. mcdanieli McGregor, T. turkestani Ugarov & Nikolski and T. urticae Koch.
Navajas Navarro, Maria +3 more
openaire +5 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Inference of Markovian properties of molecular sequences from NGS data and applications to comparative genomics [PDF]
Bioinformatics, 2015 Abstract Motivation: Next-generation sequencing (NGS) technologies generate large amounts of short read data for many different organisms. The fact that NGS reads are generally short makes it challenging to assemble the reads and reconstruct the original genome sequence.
Jie Ren +5 more
openaire +4 more sources
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
The adsorption of adsorbable organic halide onto biological solids : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Technology in Environmental Engineering [PDF]
, 1994 Chlorinated organic molecules may be removed from wastewaters by adsorption onto the biomass present in biological treatment systems. This study assessed the adsorption onto biological solids of Adsorbable Organic Halide (AOX) from two New Zealand kraft ...
Gapes, Daniel James
core
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Evolutionary descent of prion genes from a ZIP metal ion transport ancestor [PDF]
, 2009 In the more than 20 years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP) have remained enigmatic.
David Westaway +4 more
core +1 more source