Results 91 to 100 of about 4,241,168 (373)
Systems biology in inflammatory bowel diseases [PDF]
, 2014 Purpose of review: Ulcerative colitis (UC) and Crohn’s Disease (CD) are the two predominant types of inflammatory bowel disease (IBD), affecting over 1.4 million individuals in the US.
Iliopoulos, D, Koukos, G, Polytarchou, C
core +1 more source
Defining HIV-1 transmission clusters based on sequence data
AIDS (London), 2017 &NA; Understanding HIV-1 transmission dynamics is relevant to both screening and intervention strategies of HIV-1 infection. Commonly, HIV-1 transmission chains are determined based on sequence similarity assessed either directly from a sequence ...
A. Hassan +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Bioinformatics Databases: State of the Art and Research Perspectives [PDF]
, 2003 Bioinformatics or computational biology, i.e. the application of mathematical and computer science methods to solving problems in molecular biology that require large scale data, computation, and analysis, is a research area currently receiving a ...
Bry, François, Kröger, Peer
core +2 more sources
GENETIC MARKERS: COMPARATIVE CLASSIFICATION OF MOLECULAR MARKERS
Овощи России, 2018 With the creation of the molecular markers allowing to carry out analysis of genotypes on the level initial genetic information – DNA, onset one of the most multifarious and one of the most large in number class of markers at the present day.
Yu. V. Chesnokov
doaj +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]
, 2009 A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ari, Eszter +4 more
core +1 more source
Methods in Ecology and EvolutionArchival DNA samples collected and analysed for a range of research and applied questions have accumulated in the laboratories of universities, government agencies and commercial service providers for decades. These DNA archives represent a valuable, yet
K. M. Sumby +4 more
doaj +1 more source
GenFlow: generic flow for integration, management and analysis of molecular biology data
Genetics and Molecular Biology, 2004 A large number of DNA sequencing projects all over the world have yielded a fantastic amount of data, whose analysis is, currently, a big challenge for computational biology.
Marcio Katsumi Oikawa +4 more
doaj +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source