Results 61 to 70 of about 4,180,047 (368)
Molecular interaction networks in the analyses of sequence variation and proteomics data [PDF]
PROTEOMICS – Clinical Applications, 2013 Protein–protein interaction networks are typically generated in standard cell lines or model organisms as it is prohibitively difficult to record large interaction datasets from specific tissues or disease models at a reasonable pace. Although the interaction data are of high confidence, they thus do not reflect in vivo relationships as such.
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Biodiversity Data Journal, 2016 We demonstrate how a classical taxonomic description of a new species can be enhanced by applying new generation molecular methods, and novel computing and imaging technologies.
Pavel Stoev +16 more
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Bootstrap confidence for molecular evolutionary estimates from tumor bulk sequencing data
Frontiers in Bioinformatics, 2023 Bulk sequencing is commonly used to characterize the genetic diversity of cancer cell populations in tumors and the evolutionary relationships of cancer clones. However, bulk sequencing produces aggregate information on nucleotide variants and their sample frequencies, necessitating computational methods to predict distinct clone sequences and their ...
Jared Huzar +7 more
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Learning the Regulatory Code of Gene Expression
Frontiers in Molecular Biosciences, 2021 Data-driven machine learning is the method of choice for predicting molecular phenotypes from nucleotide sequence, modeling gene expression events including protein-DNA binding, chromatin states as well as mRNA and protein levels.
Jan Zrimec +6 more
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AlphaFold Protein Structure Database for Sequence-Independent Molecular Replacement
Crystals, 2021 Crystallographic phasing recovers the phase information that is lost during a diffraction experiment. Molecular replacement is a commonly used phasing method for crystal structures in the protein data bank.
Lawrence Chai +7 more
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, 2010 Background and aims Recent studies have adopted a broad definition of Sapindaceae that includes taxa traditionally placed in Aceraceae and Hippocastanaceae, achieving monophyly but yielding a family difficult to characterize and for which no obvious ...
S. Buerki +5 more
semanticscholar +1 more source
Homologous Pairing between Long DNA Double Helices
, 2016 Molecular recognition between two double stranded (ds) DNA with homologous sequences may not seem compatible with the B-DNA structure because the sequence information is hidden when it is used for joining the two strands.
Mazur, Alexey K.
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Phylogeny of Kinorhyncha Based on Morphology and Two Molecular Loci. [PDF]
PLoS ONE, 2015 The phylogeny of Kinorhyncha was analyzed using morphology and the molecular loci 18S rRNA and 28S rRNA. The different datasets were analyzed separately and in combination, using maximum likelihood and Bayesian Inference.
Martin V Sørensen +6 more
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The EM Algorithm and the Rise of Computational Biology [PDF]
, 2010 In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link +3 more
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The Plant Genome, 2015 Molecular characterization of events is an integral part of the advancement process during genetically modified (GM) crop product development. Assessment of these events is traditionally accomplished by polymerase chain reaction (PCR) and Southern blot ...
Gina M. Zastrow-Hayes +9 more
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