Scientific Reports, 2017 Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast ...
Changhyeong Yoon +7 more
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Do Osmolytes Impact the Structure and Dynamics of Myoglobin?
Molecules, 2018 Osmolytes are small organic compounds that can affect the stability of proteins in living cells. The mechanism of osmolytes’ protective effects on protein structure and dynamics has not been fully explained, but in general, two possibilities have ...
Dorota Kossowska +2 more
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Label-free differentiation of human pancreatic cancer, pancreatitis, and normal pancreatic tissue by molecular spectroscopy. [PDF]
J Biomed Opt, 2022 Teske C +6 more
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria. [PDF]
Sci Rep, 2021 Bernini A +5 more
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Laboratory spectroscopy of allylimine and tentative detection towards the G+0.693-0.027 molecular cloud [PDF]
, 2022 D. Alberton +12 more
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Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Polymer Thin Films as Universal Substrates for Extreme Ultraviolet\n Absorption Spectroscopy of Molecular Transition Metal Complexes [PDF]
, 2021 Yusef Shari’ati, Josh Vura‐Weis
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Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Vibrational Molecular Spectroscopy as a Tool to Study Molecular Structure Features of Cool-Season Chickpeas Impacted by Varieties and Thermal Processing in Relation to Nutrient Availability in Ruminants. [PDF]
Animals (Basel), 2023 Cerna L, Espinosa MER, Zhang W, Yu P.
europepmc +1 more source