Results 1 to 10 of about 2,123,606 (402)
Molecular targeted therapy for anticancer treatment. [PDF]
Exp Mol Med, 2022 Since the initial clinical approval in the late 1990s and remarkable anticancer effects for certain types of cancer, molecular targeted therapy utilizing small molecule agents or therapeutic monoclonal antibodies acting as signal transduction inhibitors ...
Min HY, Lee HY.
europepmc +4 more sources
Molecular targeted therapy: A new avenue in glioblastoma treatment. [PDF]
Oncol Lett, 2023 Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the most prevalent type of malignant brain tumor.
El Atat O +4 more
europepmc +2 more sources
Molecular targeted therapy of glioblastoma. [PDF]
Cancer Treatment Reviews, 2019 Glioblastomas are intrinsic brain tumors thought to originate from neuroglial stem or progenitor cells. More than 90% of glioblastomas are isocitrate dehydrogenase (IDH)-wildtype tumors. Incidence increases with age, males are more often affected. Beyond rare instances of genetic predisposition and irradiation exposure, there are no known glioblastoma ...
É. Le Rhun +7 more
semanticscholar +5 more sources
The advanced development of molecular targeted therapy for hepatocellular carcinoma. [PDF]
Cancer Biol Med, 2022 Hepatocellular carcinoma (HCC), one of the most common malignant tumors in China, severely threatens the life and health of patients. In recent years, precision medicine, clinical diagnoses, treatments, and innovative research have led to important ...
Yan T +11 more
europepmc +2 more sources
Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy. [PDF]
Mol Biol RepDespite the availability of technological advances in traditional anti-cancer therapies, there is a need for more precise and targeted cancer treatment strategies.
Zafar A, Khan MJ, Abu J, Naeem A.
europepmc +2 more sources
Molecular Targeted Therapy and Immunotherapy for Myelodysplastic Syndrome. [PDF]
Int J Mol Sci, 2021 Myelodysplastic syndrome (MDS) is a heterogeneous, clonal hematological disorder characterized by ineffective hematopoiesis, cytopenia, morphologic dysplasia, and predisposition to acute myeloid leukemia (AML).
Lee P +5 more
europepmc +2 more sources
Nanomaterials Enhance the Immunomodulatory Effect of Molecular Targeted Therapy. [PDF]
Int J Nanomedicine, 2021 Molecular targeted therapy, a tumor therapy strategy that inhibits specific oncogenic targets, has been shown to modulate the immune response. In addition to directly inhibiting the proliferation and metastasis of tumor cells, molecular targeted drugs ...
Li Z, Liu Y, Fang X, Shu Z.
europepmc +2 more sources
Apatinib for molecular targeted therapy in tumor
Drug Design, Development and Therapy, 2015 As tumor angiogenesis is one of the hallmarks of cancer, the inhibition of vascular endothelial growth factor signaling has become an attractive anticancer approach.
Haijun Zhang
semanticscholar +6 more sources
Targeted molecular therapies in thyroid carcinoma [PDF]
Arquivos Brasileiros de Endocrinologia & Metabologia, 2009 Thyroid cancer incidence has significantly increased in the last three decades and many patients seek medical attention for its treatment every year. Among follicular cell-derived tumors, the majority are differentiated thyroid carcinomas (DTC), whose prognosis is very good with only 15% of the cases presenting disease persistence or recurrence after ...
Serena Romagnoli +3 more
openalex +7 more sources
Pathology confronts molecular targeted therapies [PDF]
Nature Clinical Practice Oncology, 2006 José Abrão Cardeal da Costa
openalex +4 more sources