Results 51 to 60 of about 2,123,606 (402)
Long non-coding RNAs in cutaneous melanoma : clinical perspectives [PDF]
, 2017 Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding ...
Brochez, Lieve +4 more
core +1 more source
Targeted Molecular Therapy of GBM
Brain Pathology, 2003 Major advances in molecular biology, cellular biology and genomics have substantially improved our understanding of cancer. Now, these advances are being translated into therapy. Targeted therapy directed at specific molecular alterations is already creating a shift in the treatment of cancer patients.
Paul S. Mischel, Timothy F. Cloughesy
openaire +3 more sources
Molecular-Targeted Therapies for Hematologic Malignancies [PDF]
Advances in Hematology, 2012 Major advances in the disciplines of hematology, genetics, biochemistry, and chemistry over the past decades have empowered investigators with the background and methods required for development of customized molecular-targeted therapies. The ability to identify signaling pathways that are dysregulated, to determine the associated mutations, and to ...
Cheng-Kui Qu +2 more
openaire +4 more sources
Unique Molecular Features in High-Risk Histology Endometrial Cancers [PDF]
, 2019 Endometrial cancer is the most common gynecologic malignancy in the United States and the sixth most common cancer in women worldwide. Fortunately, most women who develop endometrial cancer have low-grade early-stage endometrioid carcinomas, and simple ...
Collins, Kaitlyn +4 more
core +1 more source
The Application of Inorganic Nanoparticles in Molecular Targeted Cancer Therapy: EGFR Targeting
Frontiers in Pharmacology, 2021 Epidermal growth factor receptor (EGFR) is an anticancer drug target for a number of cancers, such as non-small cell lung cancer. However, unsatisfying treatment effects, terrible side-effects, and development of drug resistance are current ...
Meng Sun +6 more
semanticscholar +1 more source
Molecular targeting of angiogenesis for imaging and therapy [PDF]
European Journal of Nuclear Medicine and Molecular Imaging, 2004 ISSN:1619 ...
Brack, Simon +2 more
openaire +5 more sources
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer [PDF]
, 2019 The response of metastatic colorectal cancer (mCRC) to the first-line conventional combination therapy is highly variable, reflecting the elevated heterogeneity of the disease.
Belardinilli, Francesca +29 more
core +1 more source
Frontiers in Genetics, 2022 Background: Given the high incidence and high mortality of cervical cancer (CC) among women in developing countries, identifying reliable biomarkers for the prediction of prognosis and therapeutic response is crucial.
Xinyu Liu +10 more
doaj +1 more source
Signal Transduction and Targeted Therapy, 2023 There is considerable potential for integrating transarterial chemoembolization (TACE), programmed death-(ligand)1 (PD-[L]1) inhibitors, and molecular targeted treatments (MTT) in hepatocellular carcinoma (HCC).
Hai-Dong Zhu +63 more
semanticscholar +1 more source
Molecular landscape of prostate cancer: implications for current clinical trials. [PDF]
, 2015 Castration-resistant prostate cancer (CRPC) is a lethal disease, and improvement with androgen-deprivation therapy has plateaued. Next-generation sequencing studies have led to significant advances in our understanding of genomic alterations in prostate ...
Ikeda, Sadakatsu +2 more
core +1 more source