Results 91 to 100 of about 15,380,906 (402)

On the onset and dispersal of a major MDR TB clone among HIV-negative patients, Tunisia

open access: yesAntimicrobial Resistance and Infection Control
Background To carry out a whole genome sequencing (WGS)-based investigation on the emergence and spread of the largest multidrug-resistant tuberculosis (MDR TB) outbreak that has been thriving among HIV-negative patients, Tunisia, since the early 2000s ...
Naira Dekhil, Helmi Mardassi
doaj   +1 more source

Delineating the evolutionary pathway to multidrug-resistant outbreaks of a Mycobacterium tuberculosis L4.1.2.1/Haarlem sublineage

open access: yesInternational Journal of Infectious Diseases
Objectives: We sought to capture the evolutionary itinerary of the Mycobacterium tuberculosis L4.1.2.1/Haarlem sublineage in northern Tunisia, where it caused a major multidrug-resistant (MDR) tuberculosis outbreak in a context strictly negative for HIV ...
Naira Dekhil, Helmi Mardassi
doaj   +1 more source

Assessment of the use and need for an integrated molecular surveillance of tuberculosis: an online survey in Germany

open access: yesBMC Public Health, 2019
Background The implementation of an integrated molecular surveillance (IMS) of tuberculosis (TB) is of high priority for TB control. IMS is defined as the systematic inclusion of molecular typing results in the national TB surveillance system.
Andrea Sanchini   +5 more
doaj   +1 more source

Development of rapid, automated diagnostics for infectious disease: advances and challenges [PDF]

open access: yes, 2009
The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Physicochemical Characteristics and Microbiological Quality of Honey Produced in Benin

open access: yesJournal of Food Quality, 2018
Honey is a very complex biological product. It has great diversity, giving it a multitude of properties, both nutritionally and therapeutically. This study aimed to study the physicochemical and microbiological characteristics of honeys collected during ...
François Ezin Azonwade   +6 more
doaj   +1 more source

Molecular epidemiology of Mycobacterium bovis in Cameroon [PDF]

open access: yes, 2017
We describe the largest molecular epidemiological study of Bovine Tuberculosis (bTB) in a sub-Saharan African country with higher spatial resolution providing new insights into bTB. Four hundred and ninety-nine samples were collected for culture from 201
Asuquo, A.   +13 more
core   +2 more sources

Multilocus microsatellite markers for molecular typing of Candida tropicalis isolates

open access: yesBMC Microbiology, 2014
Candida tropicalis is considered to be the leading pathogen causing nosocomial fungemia and hepatosplenic fungal infections in patients with cancer, particularly those with leukemia.
Yuan Wu   +7 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multiple Locus Variable number of tandem repeat Analysis : a molecular genotyping tool for Paenibacillus larvae [PDF]

open access: yes, 2016
American Foulbrood, caused by Paenibacillus larvae, is the most severe bacterial disease of honey bees (Apis mellifera). To perform genotyping of P.larvae in an epidemiological context, there is a need of a fast and cheap method with a high resolution ...
Alippi   +40 more
core   +2 more sources

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