Results 191 to 200 of about 10,024 (235)
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Pharmacokinetics of Molnupiravir in Cats with Naturally Occurring Feline Infectious Peritonitis

Pathogens
Antiviral drugs like EIDD-2801 (molnupiravir; MPV) have been successfully used in the treatment of feline infectious peritonitis (FIP). The previous study of the pharmacokinetics of MPV in healthy cats showed promise for its use and safety. The objective
P. Černá   +5 more
semanticscholar   +1 more source

Chemists shorten synthesis of molnupiravir

C&EN Global Enterprise, 2021
Chemists have developed an environmentally friendly route for making the investigational antiviral compound molnupiravir from commodity chemicals in just three steps with 69% overall yield.
openaire   +1 more source

The new cocrystal of molnupiravir-caprolactam discovered by melt crystallization with improved tableting properties.

International journal of pharmaceutics
Molnupiravir (MPV) is an oral antiviral drug widely used for the treatment of coronavirus disease 2019 (COVID-19). However, the commercial form I of MPV has a poor tabletability, greatly restricting its manufacture. To solve this problem, a new cocrystal
Peizhuo Han   +11 more
semanticscholar   +1 more source

Degree-Based and Neighborhood Degree Sum-Based Entropy Measures of Molnupiravir

Scientific Annals of Computer Science
An entirely novel virus that causes severe acute respiratory syndrome began to spread around the world at the end of 2019. Since there are no curative treatments to treat the viral infection, efforts are being made globally to stop the coronavirus from ...
Shibsankar Das   +2 more
semanticscholar   +1 more source

Pharmacokinetics and bioequivalence of a molnupiravir tablet formulation compared with the molnupiravir capsule formulation in healthy adult participants—a randomized, open-label, three-period, crossover study

Antimicrobial Agents and Chemotherapy
Molnupiravir, a prodrug of β-D-N4-hydroxycytidine (NHC), is administered orally as four 200 mg capsules twice daily for 5 days to treat COVID-19. This randomized, open-label, four-treatment sequence, three-period crossover study (NCT06615869) evaluated ...
Julie L. Fiore   +9 more
semanticscholar   +1 more source

Development of molnupiravir and peramivir loaded liposome formulations for combined antiviral therapy

Pharmaceutical development and technology (Print)
The pandemic caused by the SARS-CoV-2 virus has led scientists to intensify research on antiviral drugs and vaccines. As a result of these studies, it was observed that molnupiravir (MLP) and peramivir (PRV) could be used against pandemic.
Hadiye Keskin   +9 more
semanticscholar   +1 more source

Real-world effectiveness and economic analysis of nirmatrelvir/ritonavir, remdesivir, and molnupiravir for treatment of COVID-19 among ambulatory patients in Thailand.

Journal of Infection and Public Health
BACKGROUND Nirmatrelvir/ritonavir, remdesivir, and molnupiravir are recommended antiviral therapies for non-severe COVID-19 patients at high risk of disease progression. This study evaluated the real-world effectiveness and economic impact of these three
Sirapat Korwiwattanakan   +2 more
semanticscholar   +1 more source

Atomistic insights into the adsorption and interaction of molnupiravir on silver nanoparticles via DFT and molecular dynamics simulations

Journal of Materials Research
Effective antiviral therapy is often limited by poor bioavailability, rapid degradation, and drug resistance. Silver nanoparticles exhibit intrinsic antiviral properties and can enhance the stability and efficacy of drugs.
Mahmood Akbari, R. Morad
semanticscholar   +1 more source

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