Results 41 to 50 of about 6,560 (205)

Molnupiravir: A new candidate for COVID‐19 treatment [PDF]

open access: yesPharmacology Research & Perspectives, 2021
AbstractThe novel coronavirus disease 2019 (COVID‐19) emerged in late December 2019 in china and has rapidly spread to many countries around the world. The effective pharmacotherapy can reduce the mortality of COVID‐19. Antiviral medications are the candidate therapies for the management of COVID‐19.
Fariba Pourkarim   +2 more
openaire   +3 more sources

Comparison of the acceptability and safety of molnupiravir in COVID-19 patients aged over and under 80 years

open access: yesAging and Health Research, 2023
Background: Molnupiravir is being widely used as a treatment for coronavirus disease 2019 (COVID-19); however, its acceptability and safety in older patients aged ≥ 80 years in real-world clinical practice is not well understood.
Kohei Fujita   +8 more
doaj   +1 more source

Use of molnupiravir: A Danish nationwide drug utilization study [PDF]

open access: yes, 2023
Purpose: To describe utilization patterns, characteristics of users and prescribers of the new oral antiviral medication, molnupiravir, indicated for mild-to-moderate COVID-19.
Jesper Hallas   +13 more
core   +1 more source

Molnupiravir—A Novel Oral Anti-SARS-CoV-2 Agent

open access: yesAntibiotics, 2021
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly resulted in a global pandemic with approximately 4 million deaths.
Ching-Chi Lee   +2 more
doaj   +1 more source

Enzyme‐mediated synthesis of Molnupiravir: paving the way for the application of biocatalysis in pharmaceutical industry

open access: yes, 2022
Molnupiravir (Lagevrio®) is an orally-administered anti-COVID-19 agent. Due to the urgency to meet the worldwide demand and the growing environmental concern, there is a need for speed in the industrial implementation of novel and efficient bioprocesses ...
Del Arco, Jon   +11 more
core   +1 more source

Antiviral activity of molnupiravir against COVID-19: a schematic review of evidences

open access: yesBulletin of the National Research Centre, 2022
Background The study was aimed at encapsulating the evidence of in vitro and in vivo antiviral activities of molnupiravir and its active form against highly pathogenic SARS-CoV-2, the pathogen responsible for COVID-19, and finding out the efficacy and ...
Shivali Singla, Sachin Goyal
doaj   +1 more source

Molnupiravir in unvaccinated patients with COVID-19 [PDF]

open access: yesDrug and Therapeutics Bulletin, 2022
Abstract Overview of: Jayk Bernal A, Gomes da Silva MM, Musungaie DB, et al. Molnupiravir for oral treatment of COVID-19 in nonhospitalized patients. NEJM. 2021;doi:10.1056/NEJMoa2116044 [Epub ahead of print 16 Dec 2021].
openaire   +2 more sources

Progress Towards a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine

open access: yes, 2021
Molnupiravir (MK-4482, EIDD-2801) is a promising orally bioavailable drug candidate for treatment of COVID-19. Herein we describe a supply-centered and chromatography-free synthesis of molnupiravir from cytidine, consisting of two steps: a
Catherine P., McGeough   +8 more
core   +1 more source

Association of Molnupiravir and Nirmatrelvir-Ritonavir with preventable mortality, hospital admissions and related avoidable healthcare system cost among high-risk patients with mild to moderate COVID-19

open access: yesThe Lancet Regional Health. Western Pacific, 2023
Summary: Background: Real-world data is currently limited on the association between oral antiviral therapy and healthcare system burden in patients with mild-to-moderate COVID-19.
Abraham Ka-Chung Wai   +15 more
doaj   +1 more source

Molnupiravir. Chuukese

open access: yes, 2021
Title from PDF caption (viewed on January 4, 2022)."OHA4029A12292021 CHUUKESE"--Running footer.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

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