Results 21 to 30 of about 120,575 (162)

Synthesis, Redox and Spectroscopic Properties of Pterin of Molybdenum Cofactors

open access: yesMolecules, 2022
Pterins are bicyclic heterocycles that are found widely across Nature and are involved in a variety of biological functions. Notably, pterins are found at the core of molybdenum cofactor (Moco) containing enzymes in the molybdopterin (MPT) ligand that ...
Kyle J. Colston, Partha Basu
doaj   +1 more source

Metal-Containing Formate Dehydrogenases, a Personal View

open access: yesMolecules, 2023
Mo/W-containing formate dehydrogenases (FDH) catalyzes the reversible oxidation of formate to carbon dioxide at their molybdenum or tungsten active sites.
Silke Leimkühler
doaj   +1 more source

Physiological Importance of Molybdate Transporter Family 1 in Feeding the Molybdenum Cofactor Biosynthesis Pathway in Arabidopsis thaliana

open access: yesMolecules, 2022
Molybdate uptake and molybdenum cofactor (Moco) biosynthesis were investigated in detail in the last few decades. The present study critically reviews our present knowledge about eukaryotic molybdate transporters (MOT) and focuses on the model plant ...
Rieke Minner-Meinen   +9 more
doaj   +1 more source

Advancing Our Understanding of Pyranopterin-Dithiolene Contributions to Moco Enzyme Catalysis

open access: yesMolecules, 2023
The pyranopterin dithiolene ligand is remarkable in terms of its geometric and electronic structure and is uniquely found in mononuclear molybdenum and tungsten enzymes.
Sharon J. Nieter Burgmayer   +1 more
doaj   +1 more source

Moonlighting Arabidopsis molybdate transporter 2 family and GSH-complex formation facilitate molybdenum homeostasis

open access: yesCommunications Biology, 2023
Molybdenum (Mo) as essential micronutrient for plants, acts as active component of molybdenum cofactor (Moco). Core metabolic processes like nitrate assimilation or abscisic-acid biosynthesis rely on Moco-dependent enzymes. Although a family of molybdate
Jan-Niklas Weber   +13 more
doaj   +1 more source

Making Moco: A Personal History

open access: yesMolecules, 2023
This contribution describes the path of my nearly forty-year quest to understand the special ligand coordinated to molybdenum and tungsten ions in their respective enzymes.
Sharon J. Nieter Burgmayer
doaj   +1 more source

The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells

open access: yesBiomolecules, 2023
Sulfur is an important element that is incorporated into many biomolecules in humans. The incorporation and transfer of sulfur into biomolecules is, however, facilitated by a series of different sulfurtransferases.
Moses Olalekan Ogunkola   +3 more
doaj   +1 more source

The Mechanisms of Molybdate Distribution and Homeostasis with Special Focus on the Model Plant Arabidopsis thaliana

open access: yesMolecules, 2023
This review article deals with the pathways of cellular and global molybdate distribution in plants, especially with a full overview for the model plant Arabidopsis thaliana.
Jan-Niklas Weber   +2 more
doaj   +1 more source

The Role of System-Specific Molecular Chaperones in the Maturation of Molybdoenzymes in Bacteria

open access: yesBiochemistry Research International, 2011
Biogenesis of prokaryotic molybdoenzymes is a complex process with the final step representing the insertion of a matured molybdenum cofactor (Moco) into a folded apoenzyme.
Meina Neumann, Silke Leimkühler
doaj   +1 more source

The effect of dietary protein restriction in a case of molybdenum cofactor deficiency with MOCS1 mutation

open access: yesMolecular Genetics and Metabolism Reports, 2021
Molybdenum cofactor deficiency (MoCD) is an autosomal recessive inborn error of metabolism that results from mutations in genes involved in molybdenum cofactor (Moco) biosynthesis.
Yu Abe   +6 more
doaj   +1 more source

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