Results 61 to 70 of about 120,575 (162)

From the Eukaryotic Molybdenum Cofactor Biosynthesis to the Moonlighting Enzyme mARC

Molecules, 2018
All eukaryotic molybdenum (Mo) enzymes contain in their active site a Mo Cofactor (Moco), which is formed by a tricyclic pyranopterin with a dithiolene chelating the Mo atom.
Manuel Tejada-Jimenez, Alejandro Chamizo-Ampudia, Victoria Calatrava, Aurora Galvan, Emilio Fernandez, Angel Llamas   +5 more
doaj   +1 more source

Expression of a constitutively active nitrate reductase increases SARS‐CoV‐2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence

Plant Biotechnology Journal, Volume 24, Issue 1, Page 204-223, January 2026.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the Spike (S) protein of Severe Acute Respiratory Syndrome Coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana, a process promoted by the co‐expression of viral silencing suppressor P19.
Louis‐Philippe Hamel, Marie‐Ève Paré, Francis Poirier‐Gravel, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Marc‐André D'Aoust, Dominique Michaud   +9 more
wiley   +1 more source

Examining the liver–pancreas crosstalk reveals a role for the molybdenum cofactor in β-cell regeneration

Life Science Alliance
Investigation of the inter-organ, pancreas–liver, crosstalk reveals a potential role of the molybdenum biosynthetic pathway in β-cell regeneration. Regeneration of insulin-producing β-cells is an alternative avenue to manage diabetes, and it is crucial ...
Christos Karampelias, Bianca Băloiu, Birgit Rathkolb, Patricia da Silva-Buttkus, Etty Bachar-Wikström, Susan Marschall, Helmut Fuchs, Valerie Gailus-Durner, Lianhe Chu, Martin Hrabě de Angelis, Olov Andersson   +10 more
doaj   +1 more source

Recent Progress in CO2 Conversion: An Overview of Catalytic Strategies for Sustainable Fuel and Chemical Synthesis

SmartMat, Volume 6, Issue 6, December 2025.
This review systematically outlines recent advances in the catalytic strategies for converting CO₂ into valuable products, including photocatalysis, electrocatalysis, CO2 hydrogenation, photothermal catalysis, non‐thermal plasma, and biocatalytic processes.
An Zhang, Yanming Cai, Liang Guo, Chao Wang, Qingbo Wa, Yanping Xu, Jian Zhou, Hongshuang Fan, Ziyun Li, Xinyue Long, Jiabei Tang, Zijian Li, Li Zhai, Zhenyu Shi, Wei Zhai, Yuhui Tian, Shuai Bi, Hao Wei, Mingliang Hu, Yang Xu, Yiran Zhang, Yu Zhang, Ruiying Ding, Junjun Li, Shuangqun Chen, Jianfeng Huang, Zhanxi Fan, Xingchen Jiao, Guigao Liu, Haiqing Wang, Haifeng Tian, Jingyu Pang, Kuncheng Zhang, Weisong Liu, Huijuan Cui, Lingling Zhang, Xiaofu Sun, Jianling Zhang, Dan Ren, Sheng Zhang, Lu Qiao, Zhe Weng, Hongmei Li, Min Liu, Miao Zhong, Lei Wang, Jun Gu, Hao Bin Wu, Bolong Huang, Weijia Zhou, Chuan Xia, Min‐Rui Gao, Changbin Zhang, Rong Cao, Wei Chen, Yuan‐Biao Huang, Yongye Liang, Ya‐Qian Lan, Guoxiong Wang, Baoyu Xia, Yujie Xiong, Xinbin Ma, Tongbu Lu, Jinhua Ye, Yi Xie, Buxing Han, Jiawei Liu, Zhicheng Zhang, Hua Zhang   +68 more
wiley   +1 more source

Maternal uniparental isodisomy is responsible for serious molybdenum cofactor deficiency

, 2010
Molybdenum cofactor (MoCo) deficiency is a rare autosomal recessive inherited metabolic disorder resulting in the combined deficiency of aldehyde oxidase, xanthine dehydrogenase, and sulfite oxidase.
Gumus, Hakan, GAMZE POYRAZOĞLU, Poyrazoglu, Gamze, HAKAN GÜMÜŞ, Engelen, John, Dundar, Munis, Caglayan, Ahmet Okay, STIJN GHESQUIERE, AHMET OKAY ÇAĞLAYAN, MUNIS DUNDAR, Ichida, Kimiyoshi, Kumandas, Sefer, KIMIYOSHI ICHIDA, HÜSEYIN PER, Ghesquiere, Stijn, Kondolot, Meda, MEDA KONDOLOT, Per, HÜSEYİN, SEFER KUMANDAŞ, JOHN ENGELEN, Per, Hueseyin   +20 more
core   +1 more source

Structural insights into putative molybdenum cofactor biosynthesis protein C (MoaC2) from Mycobacterium tuberculosis H37Rv.

PLoS ONE, 2013
The Molybdenum cofactor (Moco) biosynthesis pathway is an evolutionary conserved pathway seen in almost all eukaryotes including the pathogenic species Mycobacterium tuberculosis.
Vijay Kumar Srivastava, Shubhra Srivastava, Ashish Arora, J Venkatesh Pratap   +3 more
doaj   +1 more source

Analysis of Non‐Coding RNAs and N6‐Methyladenosine‐Modified Genes in Response to flg22 in Grape Immunity

Plant Biotechnology Journal, Volume 23, Issue 12, Page 5435-5455, December 2025.
ABSTRACT Grape (Vitis vinifera) is susceptible to fungal pathogens and, consequently, severe yield losses. Investigating the immune mechanisms of the disease‐resistant Chinese wild grapes is crucial for developing sustainable disease resistance technologies.
Ruiwei Duan, Yang Feng, Runxin Zhang, Wenjing Lu, Qingqing Xie, Dong Duan   +5 more
wiley   +1 more source

Integrated Analysis of Molybdenum Nutrition and Nitrate Metabolism in Strawberry

Frontiers in Plant Science, 2020
Molybdenum (Mo) is a component of the Mo cofactor (Moco) of nitrate reductase (NR) and is therefore essential for nitrate metabolism. However, little is known about Mo deficiency phenotypes or about how physiological and molecular mechanisms of Mo uptake
Li Liu, Hongmei Shi, Shaoxuan Li, Mingyue Sun, Rui Zhang, Yongmei Wang, Fengshan Ren   +6 more
doaj   +1 more source

ThiF‐Like Enzyme Chemistry in Primary and Secondary Metabolism

ChemBioChem, Volume 26, Issue 21, November 8, 2025.
ThiF‐like enzymes are a widespread protein family found in disparate biosynthetic pathways. They are unified by their use of an NTP to modify a carboxylate, generating an activated species prone to nucleophilic addition. This common intermediate is then targeted by diverse nucleophiles, including persulfide or amino acid side chains, to yield a variety
Keelie S. Butler, Anshul Rajput, Jonathan R. Chekan   +2 more
wiley   +1 more source

Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy

EMBO Molecular Medicine, 2015
Synaptic inhibition is essential for shaping the dynamics of neuronal networks, and aberrant inhibition plays an important role in neurological disorders.
Borislav Dejanovic, Tania Djémié, Nora Grünewald, Arvid Suls, Vanessa Kress, Florian Hetsch, Dana Craiu, Matthew Zemel, Padhraig Gormley, Dennis Lal, EuroEPINOMICS Dravet working group, Candace T Myers, Heather C Mefford, Aarno Palotie, Ingo Helbig, Jochen C Meier, Peter De Jonghe, Sarah Weckhuysen, Guenter Schwarz   +18 more
doaj   +1 more source