Results 101 to 110 of about 37,127 (223)

Implementation of Nano Flow Chromatography Coupled to Mass Spectrometry as a Reliable and Sensitive Discovery Lipidomics Platform

Rapid Communications in Mass Spectrometry, Volume 40, Issue 23, 15 December 2026.
ABSTRACT Rationale Untargeted lipidomics is commonly performed at analytical flow rates, which consume more solvent and may require higher on‐column sample loads when sensitivity is limited by analyte abundance. Nano flow separations use lower flow rates and sample loads, reducing solvent consumption and facilitating improved electrospray ionization ...
Ciara J. Sallowicz, Thiago Mattos, Rahul R. Deshpande, Bashar Amer, Susan S. Bird   +4 more
wiley   +1 more source

Of Mice and MAGL (Monoacylglycerol Lipase)

The FASEB Journal, 2011
About 18.8 million American adults suffer depressive disorders that may occur with anxiety and substance abuse. Tetrahydrocannabinol (THC), a compound in marijuana, is a cannabinoid chemical that binds to and activates cannabinoid receptors (CB1) in the pre‐synaptic cell membrane as part of neuron‐to‐neuron transmission in the ...
S. Bach, T. Bombinski, M. Daniels, D. Gross, T. Hogg, T. Martin, D. McMurray, E. Naber, N. Perez, A. Schulman, S. Tucker, S. Andera‐Cato, A. Arnold, A. Blumberg, M. Bord, A. Feiertag, M. Greaves, A. Her, E. Kennedy, C. Orozco, C. Rice, A. Rodgers, A. Sauer, J. Schubert, C. Tubbs, T. Wray, G. Vogt, L. Shrestha, C. Hillard   +28 more
openaire   +1 more source

Produção de mono e diacilgliceróis a partir da glicerólise enzimática de óleo de oliva [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2010Este trabalho apresenta dados experimentais referentes à glicerólise de óleo de oliva usando a enzima ...
Krüger, Roberta Letícia
core  

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10459-10474, November 2026.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera

eFood, Volume 7, Issue 5, October 2026.
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana, Julia da Costa Santos, Ana Caroline de Medeiros Dantas, David Henrique Xavier Barbosa, Matheus de Freitas Fernandes Pedrosa, Pablo Felipe Ferreira Farias, Susana Margarida Gomes Moreira, Patrícia Prado Augusto, Patricia Santos Lopes, Ana Paula Barreto Gomes, Rui de Oliveira Macedo, Francisco Canindé de Sousa Júnior, Cristiane Fernandes de Assis   +12 more
wiley   +1 more source

A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance

Diabetes, Metabolic Syndrome and Obesity, 2009
Hidekatsu Yanai1,2, Yoshiharu Tomono3, Kumie Ito1,2, Yuji Hirowatari4, Hiroshi Yoshida1,5, Norio Tada1,21Department of Internal Medicine, 2Institute of Clinical Medicine and Research, 3Department of Nutrition, 5Department of Laboratory Medicine, Jikei ...
Yanai H
doaj   +2 more sources

Simultaneous Overcoming Approach for Poor Wettability and Low Stability in Stomach by Simple Methods; Formulation Design and Development of Monoacylglycerol Acyltransferase 2 Inhibitor, S-309309 [PDF]

N-[(4R)-5,7-difluoro-2\u27-(5-methylpyridin-2-yl)-4\u27-oxo-2,2\u27,3,4\u27,5\u27,7\u27-hexahydrospiro[1-benzopyran-4,6\u27-pyrazolo[4,3-c]pyridin]-3\u27-yl]-2-(methanesulfonyl)acetamide (S-309309) is an anti-obesity drug developed by Shionogi & Co., Ltd.
Atsushi, Inoue, Takeshi, Funaki, Yuta, Nakagawa, Masato, Gomi, Shojiro, Shimokawa   +4 more
core   +1 more source

Bio‐guided fractionation of (9Z )‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

Journal of the Science of Food and Agriculture, Volume 106, Issue 13, Page 7735-7746, October 2026.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai, Nguyen Van Quan, Nguyen Dang Duc, Tran Dang Xuan   +3 more
wiley   +1 more source

Monoacylmonoalkylglycerol as a substrate for diacylglycerol hydrolase activity in adipose tissue.

Journal of Lipid Research, 1978
The synthesis and use of 1(3)-[3H]oleoyl-2-0-oleylglycerol as a substrate for the assay of diacylglycerol hydrolase activity in adipose tissue is described.
H Tornqvist, P Björgell, L Krabisch, P Belfrage   +3 more
doaj   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source