Results 91 to 100 of about 37,127 (223)

Monoacylglycerol lipase inhibition-induced changes in plasma corticosterone levels, anxiety and locomotor activity in male CD1 mice [PDF]

, 2013
The hypothalamus-pituitary-adrenal-axis is strongly controlled by the endocannabinoid system. The specific impact of enhanced 2-arachidonoylglycerol signaling on corticosterone plasma levels, however, was not investigated so far.
Aliczki, Manó, Varga, Zoltán K., Mikics, Éva, Bakos, Nikoletta Venczkone, Pintér, Ottó, Varga, János, Zelena, Dóra, Haller, József   +7 more
core   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

Tapetal Expression of BnaC.MAGL8.a Causes Male Sterility in Arabidopsis

Frontiers in Plant Science, 2019
Monoacylglycerol lipase (MAGL) hydrolyzes monoacylglycerol, producing free fatty acid and glycerol. Although this enzyme has been shown to play important roles in mammal, its potential function in plants remains poorly understood. In a survey of the MAGL
Jie Gao, Qun Li, Nan Wang, Baolong Tao, Jing Wen, Bin Yi, Chaozhi Ma, Jinxing Tu, Tingdong Fu, Qiang Li, Jitao Zou, Jinxiong Shen   +11 more
doaj   +1 more source

Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors [PDF]

, 2018
Monoacylglycerol lipase (MAGL) is the enzyme hydrolyzing the endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid and glycerol.
Carlson, Kathryn E., Giannotti, Massimiliano, Chicca, Andrea, Lapillo, Margherita, Granchi, Carlotta, Katzenellenbogen, John A., Carlson, Kathryn E, Minutolo, Filippo, Kim, Sung Hoon, Bononi, Giulia, Poli, Giulio, Martinelli, Adriano, Katzenellenbogen, John A, Tuccinardi, Tiziano, Nieri, Daniela, Rizzolio, Flavio, Caligiuri, Isabella, Macchia, Marco, Boustani, Maguie El, Fortunato, Serena   +19 more
core   +2 more sources

Polar Lipid and Fatty Acid Profiles of Oat Groats Substantially Influenced by Field Management: A Comparison of Cultivars, Sowing Times and Fertilizer Composition

Plant, Cell &Environment, EarlyView.
ABSTRACT The polar lipids in oat grains are crucial due to their biological functions, nutritional quality, potential use in food flavour and processing, the protection they provide against biotic and abiotic stresses, and their ability to act as cellular signalling molecules.
Syed Rehmat Ullah Shah, Lena Engström, Carl Grey, Anders Jonsson, Johanna Wetterlind, Cecilia Tullberg   +5 more
wiley   +1 more source

Ontogeny of microsomal activities of triacylglycerol synthesis in guinea pig liver.

Journal of Lipid Research, 1987
Because the onset of triacylglycerol-rich lipoprotein synthesis occurs in guinea pig liver during fetal life, we investigated the microsomal enzyme activities of triacylglycerol synthesis in fetal and postnatal guinea pig liver.
R A Coleman, E B Haynes, C D Coats
doaj   +1 more source

Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors [PDF]

, 2018
Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays an important role in the degradation of the endocannabinoid neurotransmitter 2-arachidonoylglycerol, which is implicated in many physiological processes.
De Stefano L., Manera, Clementina, Rizzolio F., Margherita Lapillo, Gertsch, Jürg, Tuccinardi T., Baraldi, Stefania, Martinelli, Adriano, Filippo Minutolo, Macchia, Marco, De Stefano, Lucia, Lorenzo Di Cesare Mannelli, Carlotta Granchi, Stefania Baraldi, Martinelli A., Flavio Rizzolio, Carla Ghelardini, Di Cesare Mannelli, Lorenzo, Di Cesare Mannelli L., Ruggiero, Emanuela, Rizzolio, Flavio, Andrea Chicca, Gertsch J., Macchia M., Mojgan Aghazadeh Tabrizi, Lapillo M., Baraldi S., Granchi, Carlotta, Marco Macchia, Baraldi, Pier Giovanni, Minutolo, Filippo, Clementina Manera, Granchi C., Ghelardini, C, Baraldi P. G., Jürg Gertsch, Aghazadeh Tabrizi M., Lucia De Stefano, Aghazadeh Tabrizi, Mojgan, Di Cesare Mannelli, L, Emanuela Ruggiero, Adriano Martinelli, Chicca, Andrea, Pier Giovanni Baraldi, Lapillo, Margherita, Manera C., Chicca A., Ghelardini C., Tuccinardi, Tiziano, Ghelardini, Carla, Ruggiero E., Tiziano Tuccinardi, Minutolo F.   +52 more
core   +2 more sources

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

The relationship between the carboxylesterase and monoacylglycerol lipase activities of chicken liver microsomes

, 1985
The carboxylesterase (carboxylic-ester hydrolase, EC 3.1.1.1) and monoacylglycerol lipase (glycerol-monoester acylhydrolase, EC 3.1.1.23) activities, measured against ethyl butyrate and emulsified monooleoylglycerol respectively, were determined for ...
de Jersey J., Zerner B., Keough D.T.
core   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source